How accurate is a negative fetal fibronectin test?
Negative fFN test result: You have a 1 to 5 percent chance of delivering in the next two weeks. Even though preterm labor is unlikely in the near term, you may be kept under observation for several hours to monitor for symptoms and further changes to your cervix.
What does a negative fFN test mean?
Negative. A negative result means that fetal fibronectin isn’t present in your cervical fluid. This indicates that you aren’t likely to deliver in the next two weeks.
Can you have a false negative fFN?
Since fFN may bind to Candida, a vaginal yeast, the results of fFN test may be falsely negative if a patient has a vaginal yeast infection.
Can the preterm labor test be wrong?
Although it’s a simple test, it’s not done for everyone because, in those who are at low risk for preterm labor, it’s generally not a helpful test. False positives are pretty common, which can add needless stress to your experience.
What can cause false positive fetal fibronectin?
A false – positive test may result from: 1) digital examination prior to the speculum exam, 2) more than a minimal amount of blood in the specimen as FFN is in plasma, 3) the presence of amniotic fluid (which contains FFN) in the specimen, or 4) the patient having had intercourse within the previous 24 hours (FFN can …
What can cause a false positive fFN test?
What is fFN test used for?
Fetal fibronectin (fFN) is used to test pregnant women who are between 22 weeks and 35 weeks of pregnancy and are having symptoms of premature labor. The test helps predict the likelihood of premature delivery within the next 7-14 days.
How long does it take to get fFN results?
You should hear the results within 24 hours. Low levels of fetal fibronectin rule out the possibility of labor within the next two weeks.
What produces fetal fibronectin?
Fetal fibronectin (fFN) is a protein produced during pregnancy. It is produced by cells at the border of the amniotic sac and the mother’s uterus, attaching the amniotic sac to the uterine lining.
What causes fetal fibronectin?
During pregnancy, a uterine infection causes inflammation, which can trigger preterm labor. This inflammation can also stimulate the amnion cells to produce fetal fibronectin, a protein. Fetal fibronectin testing is sometimes done when preterm labor symptoms are present.
How long is fFN test good for?
The fFN test may be repeated after 2 weeks if the first fFN is negative and labor symptoms persist beyond the next 7 to 14 days. The test may therefore be repeated several times since each test result is valid for the following 7 to 14 days.
What is the accuracy of the fFN test?
Positive predictive value, negative predictive value, and accuracy of AmniSure test to diagnose PROM were 98.2, 97.3, and 97.7 %, respectively, compared with 89.7, 94.2, and 91.8 %, respectively, for fFN test.
What happens if the fetal fibronectin test is negative?
If the fetal fibronectin test is positive, your health care provider will take steps to address premature birth — such as administering medication to enhance the baby’s lung maturity. If the fetal fibronectin test is negative, you can be assured that you’re unlikely to deliver within the next two weeks.
Which is better FFN or Nitrazine or ferning?
fFN bedside test is better than nitrazine and ferning tests in detection of PROM, but is not suited for identification of clinically difficult cases with suspected PROM, because, it is influenceable and can give false-positive results in preterm labor, women >34 gestational weeks and after any vaginal manipulation without PROM.
What are the results of the amnisure test?
Results: Sensitivity and specificity of AmniSure test to diagnose PROM were 97.3 and 98.2 %, respectively, compared with 94.5 and 89.1 %, respectively, for fFN test.