What is dextromethorphan and how does it work?
What Is Dextromethorphan and How Does It Work? Dextromethorphan is an over-the-counter ( OTC) medication used to treat cough.
What is the generic name for dextromethorphan HBr?
Generic Name: dextromethorphan HBr This medication is used for temporary relief of coughs without phlegm that are caused by certain infections of the air passages (e.g., sinusitis , common cold ).
What’s the difference between dextromethorphan and guaifenesin?
Dextromethorphan is a cough suppressant. Guaifenesin is an expectorant. Dextromethorphan and guaifenesin is a combination medicine used to treat cough and chest congestion caused by the common cold or allergies.
Can you take dextromethorphan over the counter alone?
It is available over-the-counter alone and is also present in many over-the-counter and prescription combination medications. Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.
What is the sterocenter configuration of dextromethorphan?
Dextromethorphan is a 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a- (epiminoethano)phenanthrene in which the sterocenters at positions 4a, 10 and 10a have S-configuration. It is a prodrug of dextrorphan and used as an antitussive drug for suppressing cough.
When was dextromethorphan first approved for medical use?
It was patented in 1949 and approved for medical use in 1953. The primary use of dextromethorphan is as a cough suppressant, for the temporary relief of cough caused by minor throat and bronchial irritation (such as commonly accompanies the flu and common cold ), as well as those resulting from inhaled particle irritants.
What’s the maximum dosage of dextromethorphan you can take?
Immediate-release: 10 to 20 mg orally every 4 hours or 30 mg orally ever 6 to 8 hours. Extended-release: 60 mg orally every 12 hours. Maximum dose: 120 mg in 24 hours.
Is it safe to give dextromethorphan to atopic children?
Because dextromethorphan can trigger a histamine release ( allergic reaction ), atopic children, who are especially susceptible to allergic reactions, should be administered dextromethorphan only if absolutely necessary, and only under the strict supervision of a healthcare professional.