What is the mechanism of diabetes mellitus?
Diabetes mellitus is a syndrome with disordered metabolism and inappropriate hyperglycemia due to either a deficiency of insulin secretion or to a combination of insulin resistance and inadequate insulin secretion to compensate.
What is the primary focus for treatment of diabetes mellitus?
The general goals of the treatment of diabetes are to avoid acute decompensation, prevent or delay the appearance of late disease complications, decrease mortality, and maintain a good quality of life.
What is well controlled diabetes?
As a person with diabetes, you’re considered well-controlled if your A1C (used to monitor how well your diabetes treatment is working over time) value is between 6.5 to 7% or lower. This also means that your average blood sugars are between 140 to 154 mg/dL.
How does insulin help diabetes?
Sometimes, people with type 2 diabetes or gestational diabetes need insulin therapy if other treatments haven’t been able to keep blood glucose levels within the desired range. Insulin therapy helps prevent diabetes complications by keeping your blood sugar within your target range.
What causes type 2 diabetes mechanism?
Type 2 Diabetes Mellitus (T2DM), one of the most common metabolic disorders, is caused by a combination of two primary factors: defective insulin secretion by pancreatic β-cells and the inability of insulin-sensitive tissues to respond appropriately to insulin.
What is the best treatment for diabetes mellitus?
Metformin is a tried and tested medicine that has been used for many decades to treat type 2 diabetes, and is recommended by most experts as first-line therapy. It is affordable, safe, effective, and well tolerated by most people. When metformin does not adequately control blood sugar, another medication must be added.
What is the best medicine for diabetes mellitus?
Metformin is generally the preferred initial medication for treating type 2 diabetes unless there’s a specific reason not to use it. Metformin is effective, safe, and inexpensive. It may reduce the risk of cardiovascular events. Metformin also has beneficial effects when it comes to reducing A1C results.
What kind of medications are used for diabetes?
MEDICATIONS. Diabetes Forecast. DRUG CLASS HOW IT PRIMARILY WORKS GENERIC NAME BRAND NAME COST* TYPE 2 ORAL MEDICATIONS Biguanides . (generic available) Lowers the amount of glucose produced by the liver Metformin Glucophage Low Metformin extended release Glucophage XR, Glumetza, Fortamet. Sulfonylureas .
Which is the best medicine to lower blood glucose?
Oral colesevelam Welchol High Dopamine-2 Agonists Help lower blood glucose levels after a meal. Oral bromocriptine (quick release) Cycloset, Parlodel High DPP-4 Inhibitors Prevent breakdown of GLP-1, a compound in the body that lowers blood glucose levels.
Which is the first line drug for T2DM?
Metformin is the first-line pharmacotherapy for T2DM. Besides reducing the glucose level, this has an insulin-sensitizing effect with multiple actions on tissues such as the liver, skeletal muscle, endothelium, adipose tissue, and the ovary. Only if after three months the levels of HbA1cis higher than 7.0%, a second medication can be added.
How are diabetes mellitus and resistance to insulin related?
About Diabetes Mellitus: Diabetes is a life-long disease marked by elevated levels of sugar in the blood. It can be caused by too little insulin (a chemical produced by the pancreas to regulate blood sugar), resistance to insulin, or both. The following list of medications are in some way related to, or used in the treatment of this condition.