Can GFR be low with normal creatinine?
GFR is the best measure of kidney function but both creatinine and GFR can be useful indicators of your kidney health. If GFR goes down, it’s a bad sign. If creatinine goes up, it’s a bad sign. In general, a “good” GFR number is above 60 and a “good” creatinine number is below 1.2.
Can you have CKD with normal creatinine?
A “Normal” Serum Creatinine Level May Not Be Normal. This perceived “normal” serum creatinine value actually corresponds to stage 3 CKD. Likewise, the rate of increase or trend of serum creatinine levels can also indicate CKD.
Why is GFR better than serum creatinine?
Creatinine clearance exceeds GFR because creati- nine is secreted by the proximal tubule as well as filtered by the glomerulus. Creatinine clearance can be measured from serum creatinine and cre- atinine excretion, or estimated from serum cre- atinine using estimating equations.
What would cause my GFR to drop?
A decrease or decline in the GFR implies progression of underlying kidney disease or the occurrence of a superimposed insult to the kidneys. This is most commonly due to problems such as dehydration and volume loss. An improvement in the GFR may indicate that the kidneys are recovering some of their function.
Can you get a false low GFR reading?
“Near the border of 60 mL/min/1.73 m2 creatinine-based eGFR can be inaccurate. More than half of patients with eGFR less than 60 have an eGFR of 45 to 60, and in that group there are a lot of false positives, meaning the eGFR based on creatinine says they have CKD, but their kidney function may be normal.
Why would GFR drop suddenly?
What medications cause low creatinine?
Certain medicines can cause creatinine clearance levels to be lower than normal. These include cimetidine, procainamide, certain antibiotics, and quinidine. Certain conditions, such as diabetes and congestive heart failure, may also affect the results.
What is the normal serum creatinine level?
Typical serum creatinine ranges are 0.5 to 1.0 milligrams per deciliter for women and 0.7 to 1.2 mg/dl for men. A serum creatinine level of 2.0 mg/dl may indicate normal kidney function in a male bodybuilder, but 0.7 mg/dl can indicate significant renal disease in a frail old woman.
What are the effects of low creatinine level?
Low creatinine can be a sign of certain diseases which cause decreased muscle mass, including myasthenia gravis and muscular dystrophy. These patients will present with weakness, muscle wasting, and other symptoms in addition to the abnormal blood levels.
What causes a low creatinine?
Causes of Low Creatinine Levels. These are the most common causes that lead to low creatinine levels: Reduced muscle mass – this can lead to decreased production of creatinine and it is encountered in elderly patients or those suffering from malnutrition, excessive weight loss or chronic illnesses.