What are enzyme transferases?
Transferases are enzymes that catalyze the transfer of a group of atoms, such as amine, carboxyl, carbonyl, methyl, acyl, glycosyl, and phosphoryl from a donor substrate to an acceptor compound.
What kind of reaction does transferases catalyze?
Transferases catalyze the transfer of functional groups such as methyl, hydroxymethyl, formal, glycosyl, acyl, alkyl, phosphate, and sulfate groups by means of a nucleophilic substitution reaction. They are not widely used in industrial processes.
What are the examples of transferases enzymes?
Classification
| EC number | Examples |
|---|---|
| EC 2.5 | riboflavin synthase and chlorophyll synthase |
| EC 2.6 | transaminase, and oximinotransferase |
| EC 2.7 | phosphotransferase, polymerase, and kinase |
| EC 2.8 | sulfurtransferase and sulfotransferase |
What does glutathione S transferase do?
Glutathione S-transferases (GSTs) are a family of Phase II detoxification enzymes that function to protect cellular macromolecules from attack by reactive electrophiles. Specifically, GSTs catalyse the conjugation of glutathione (GSH) to a wide variety of endogenous and exogenous electrophilic compounds (Figure 1).
What are the function of transferases?
Transferases are enzymes that catalyse the transfer of a functional group from a donor molecule, often a coenzyme, to an acceptor molecule.
What is km substrate concentration?
For practical purposes, Km is the concentration of substrate which permits the enzyme to achieve half Vmax. An enzyme with a high Km has a low affinity for its substrate, and requires a greater concentration of substrate to achieve Vmax.”
Is glutathione an enzyme?
Glutathione is manufactured in the liver after ingestion of the appropriate amino acids and sulfur-containing foods. This underappreciated water-soluble compound serves as an antioxidant and regenerator of vitamin E and carotenoids, as well as an intracellular enzyme.
What is the major biochemical function of glutathione?
Biochemical Functions of Glutathione S-Transferase Family of Salix babylonica. Glutathione S-transferases (GSTs) are ubiquitous enzymes that are encoded by a large gene family, and they contribute to the detoxification of endogenous or xenobiotic compounds and oxidative stress metabolism in plants.
What is the reaction of a transferase enzyme?
Transferases (EC 2.x.x.x) are a class of enzymes that transfer the specific functional groups from one molecule (called the donor) to another (called the acceptor). The reaction is: A + BX → AX + B.
What kind of groups are transferred by transferase?
Phosphate, methyl (−CH3), and sulfur-containing groups are among the other groups transferred by the action of these enzymes. For the large and important group of enzymes that catalyze the transfer of hydrogen, see oxidoreductase.
How many transferase enzymes are there in the world?
Transferase, any one of a class of more than 450 enzymes that catalyze the transfer of various chemical groups (other than hydrogen) from one compound to another.
Which is the enzyme that transfers functional groups from one molecule to another?
Transferases (EC 2.x.x.x) are a class of enzymes that transfer the specific functional groups from one molecule (called the donor) to another (called the acceptor).