What is the normal range of HBV DNA quantitative?
Normal range for this assay is Not Detected. The quantitative range of this assay is 1.00-9.00 log IU/mL (10-1,000,000,000 IU/mL).
What is HBV quantitative PCR?
Background/aims: To investigate whether the measurement of HBV DNA by quantitative polymerase chain reaction (PCR) is helpful in monitoring response to interferon treatment in chronic hepatitis B virus infection, we have determined sequentially serum levels of HBV DNA during and up to 18 months after treatment, in 10 …
What HBV DNA level is high?
A baseline high HBV-DNA level > 10 000 copies/mL was associated with a significant increased risk of HCC[30] and with progression towards cirrhosis[22].
What is HBsAg quantification?
It has been suggested that hepatitis B surface antigen (HBsAg) quantification reflects the concentration of cccDNA in the liver. In hepatitis B e antigen (HBeAg) positive chronic hepatitis B, HBsAg levels are higherduring the immune tolerance phase than during the immune clearance phase.
What does HBV DNA detected mean?
The presence of HBV DNA in serum is a reliable marker of active HBV replication. HBV DNA levels are detectable by 30 days following infection, generally reach a peak at the time of acute hepatitis, and gradually decrease and disappear when the infection resolves spontaneously.
What is HBV viral load?
The hepatitis B virus DNA quantification, also known as the viral load test, is a blood test that measures the amount of hepatitis B virus DNA (viral load) in the blood of chronically infected patients. The blood is tested using a Polymerase Chain Reaction (PCR) technique.
What is HBsAg qualitative test?
The ARCHITECT HBsAg Qualitative assay is a chemiluminescent microparticle immunoassay (CMIA) for the qualitative detection of hepatitis B surface antigen (HBsAg) in human serum and plasma. SUMMARY AND EXPLANATION OF TEST. The causative agent of serum hepatitis is hepatitis B virus (HBV) which is an enveloped DNA virus.
When is HBV DNA positive?
A positive HBV-DNA level (greater than 115 copies of the virus per mL [> 20 IU/mL]) indicates that the virus is multiplying in the individual’s body and the person is contagious. The test is most often used to monitor the efficacy of antiviral therapy in individuals with chronic HBV infection.
What is HBV DNA log?
A quantitative result expressed in IU/mL and log IU/mL indicates the degree of active HBV viral replication in the patient. Monitoring HBV DNA levels over time is important for assessing disease progression or monitoring a patient’s response to anti-HBV therapy.
What is normal range of HBV DNA?
Quantitative Range: 20 – 170,000,000 IU/mL (1.3 – 9.2 Log IU/mL) 1 IU/mL of HBV DNA is approximately 5.82 copies/mL A negative result (“Not Detected”) does not rule out the presence of HBV below the limit of detection of the assay or the presence of inhibitory substances. HBV viral loads detected at less than 20 IU/mL are not quantitated.
What is hepatitis B DNA test?
Hepatitis B DNA test: This is a highly sophisticated blood test that checks for the presence of hepatitis B virus DNA in the bloodstream. The DNA test indicates how much virus is present in the blood.
What is an anti DNA?
Anti-DNA is an immunoglobulin specific against native (double-stranded) DNA. It is increased in Systemic lupus erythematosus & is highly specific to SLE.