What is a high tTG IgA level?
Presence of the tissue transglutaminase (tTG) IgA antibody is associated with glutensensitive enteropathies such as celiac disease and dermatitis herpetiformis. tTG IgA antibody concentrations greater than 40 U/mL usually correlate with results of duodenal biopsies consistent with a diagnosis of celiac disease.
What does high tissue transglutaminase IgA mean?
Interpretation. The finding of tissue transglutaminase (tTG)-IgA antibodies is specific for celiac disease and possibly for dermatitis herpetiformis. For individuals with moderately to strongly positive results, a diagnosis of celiac disease is likely and the patient should undergo biopsy to confirm the diagnosis.
What does high anti gliadin IgA mean?
What does it mean if your Anti-gliadin IgA result is too high? The presence of fecal antigliadin antibodies can indicate an immune response (in the gut) to gluten in the diet. Gliadin is a component of gluten, the protein found in wheat and other field grass grains such as barley, malt, and rye.
What is a normal celiac level?
For example, at the Celiac Center at Beth Israel Deaconess Medical Center (BIDMC), the reference range is 0-19 units. A person with celiac disease who is carefully following the gluten-free diet should expect to see the TTG IgA number fall < 20 and remain there.
What is tTG IgA?
A tissue transglutaminase IgA (tTg-IgA) test is used to help doctors diagnose celiac disease. In this autoimmune disorder, the immune system mistakenly thinks that gluten — a protein in wheat, barley, rye, and oats — is a foreign invader.
What is a low tTG IgA level?
Negative: <15 U/mL. Positive: 15 U/mL or greater. This testing reflexes automatically to tissue transglutaminase IgG if total IgA is too low. In these cases, tissue transglutaminase IgA will be resulted as “LOW IGA” and the charges credited.