What can leave the nucleus?
RNA/DNA can leave the nucleus. mRNA is made during transcription/translation.
What happens to the transcript before it leaves the nucleus?
Transcription takes place in the nucleus. It uses DNA as a template to make an RNA molecule. RNA then leaves the nucleus and goes to a ribosome in the cytoplasm, where translation occurs. Translation reads the genetic code in mRNA and makes a protein.
What 3 modifications must happen to the mRNA before it can leave the nucleus?
The pre-mRNA has to go through some modifications to become a mature mRNA molecule that can leave the nucleus and be translated. These include splicing, capping, and addition of a poly-A tail, all of which can potentially be regulated – sped up, slowed down, or altered to result in a different product.
What happens after the mRNA goes out of the nucleus?
The mRNA directs the synthesis of proteins, which occurs in the cytoplasm. mRNA formed in the nucleus is transported out of the nucleus and into the cytoplasm where it attaches to the ribosomes. Proteins are assembled on the ribosomes using the mRNA nucleotide sequence as a guide.
Why can RNA leave the nucleus?
Explanation: Messenger RNA, or mRNA, leaves the nucleus through pores in the nuclear membrane. These pores control the passage of molecules between the nucleus and the cytoplasm.
What Cannot leave the nucleus?
DNA, which contains our genetic code, is located inside the nucleus of eukaryotic organisms. DNA cannot leave the nucleus, and so to send instructions to the rest of the cell it has to be replicated, creating mRNA, which can leave the nucleus.
What modifications may occur to an RNA before it leaves the nucleus?
What types of modifications may occur to this RNA before it leaves the nucleus? The RNA needs a GTP cap added to the 5′ end, a polyA tail added to the 3′ end. Also, splicing must occur, where the spliceosome must attach to the introns and remove them.
How is pre-mRNA processed before leaving the nucleus?
Messenger RNA, or mRNA, leaves the nucleus through pores in the nuclear membrane. During mRNA processing, the introns (non-coding regions) of the pre-mRNA are removed, and the exons (the coding regions) are spliced together. Additionally, a 5′ cap and a 3′ poly A tail are added to the pre-mRNA.
How is mRNA modified before leaving the nucleus?
How may mRNA be modified before it leaves the nucleus? Before mRNA leaves the nucleus of a eukaryotic cell, a cap is added to one end of the molecule, a poly A tail is added to the other end, introns are removed, and exons are spliced together. During translation the amino acids are assembled into a protein.
How does mRNA leave the nucleus?
Messenger RNA, or mRNA, leaves the nucleus through pores in the nuclear membrane. These pores control the passage of molecules between the nucleus and the cytoplasm. Before the mRNA arrives in the cytoplasm, however, it must be processed.
How are eukaryotic Mrnas modified before leaving the nucleus?
How is eukaryotic RNA processed before leaving the nucleus?
Before leaving the nucleus as mRNA, eukaryotic transcripts are modified or processed in several ways. Both exons and introns are transcribed from DNA into RNA. However before the RNA leaves the nucleus the introns are removed and the exons are joined to produce an mRNA molecule with a continuous coding sequence.
Where does the mRNA go after it leaves the nucleus?
Ribosomes appear both free in the cell cytoplasm and attached to a membranous organelle called the endoplasmic reticulum, both of which lie outside the nucleus. Before the mRNA can pass through the double plasma membrane that makes up the nuclear envelope (or nuclear membrane), it must reach the membrane somehow.
How is the nucleus important to the cell?
The nucleus needs to protect the all-important genetic material of the cell, yet it also must have a means of exchanging proteins and nucleic acids with the cell cytoplasm. This is accomplished via “gates” consisting of proteins and known as nuclear pore complexes (NPC).
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How is DNA passed from nucleus to cytoplasm?
Nuclear Membrane. If the massive DNA double helix passed back and forth from the nucleus to construct the proteins in the cytoplasm, the complex molecules easily could be corrupted. Pores perforate the nuclear membrane, regulating the passage of molecules between the nucleus and the cytoplasm.