What is the main cause of pathogenesis in Streptococcus pneumoniae?
Pneumococcal surface proteins: S. pneumoniae has a large variety of surface-exposed proteins (17, 72) that aid in its pathogenesis by acting as adhesins to host cells and hindering the host’s immune system, specifically the complement system (22, 27, 51, 145, 146).
What is the pathogenicity of Streptococcus pneumoniae?
Streptococcus pneumoniae (the pneumococcus) is the classic example of a highly invasive, Gram-positive, extracellular bacterial pathogen. It is a major cause of morbidity and mortality globally causing more deaths than any other infectious disease.
What type of pathogen is pneumococcal?
Pneumococcal [noo-muh-KOK-uhl] disease is a name for any infection caused by bacteria called Streptococcus pneumoniae, or pneumococcus. Pneumococcal infections can range from ear and sinus infections to pneumonia and bloodstream infections. There are vaccines to help prevent pneumococcal disease.
How does strep pneumonia cause pneumonia?
Pneumococcal disease is caused by common bacteria (Streptococcus pneumoniae) that can attack different parts of the body. When these bacteria invade the lungs, they can cause pneumonia; when they invade the bloodstream, they can cause sepsis; and when they invade the covering of the brain, they can cause meningitis.
Is pneumococcal pneumonia viral or bacterial?
Pneumococcal pneumonia is caused by bacteria, not a virus. The bacteria that cause pneumococcal pneumonia are called Streptococcus pneumoniae. These bacteria can spread from person to person through coughing or close contact.
What is the difference between pneumonia and pneumococcal pneumonia?
Pneumonia is a lung disease. Pneumococcal pneumonia, a kind of pneumonia, can infect the upper respiratory tract and can spread to the blood, lungs, middle ear, or nervous system.
What are the characteristics of streptococcus pneumonia?
Streptococcus pneumoniae, or pneumococcus, is a Gram-positive, spherical bacteria, alpha-hemolytic (under aerobic conditions) or beta-hemolytic (under anaerobic conditions), aerotolerant anaerobic member of the genus Streptococcus. They are usually found in pairs (diplococci) and do not form spores and are non motile.
How is the pathophysiology of pneumonia characterized?
The pathophysiology of pneumonia is characterized by four stages. The first stage of the disease occurs within 24 hours of infection and it is distinguished by vascular congestion and alveolar edema. The lungs are also invaded by bacteria and few neutrophils. Typical symptoms include:
What is the pathophysiology of a lung infection?
Pathophysiology of pneumonia. Pneumonia is an inflammatory disease of the lungs, characterized by inflammation of the parenchyma of the lungs, or alveoli, and abnormal alveolar filling with fluid.
How is the parenchyma of the lung affected by pneumonia?
Pneumonia is a lung condition wherein the parenchyma of the lung becomes inflamed. The inflammation could occur due to a bacterial, viral, or fungal infection. At times, one may develop this infection after being admitted to a hospital for the treatment of another condition.
How is pneumonia caused by a microbial agent?
Pneumonia indicates an inflammatory process of the lung parenchyma caused by a microbial agent. The most common pathway for the microbial agent to reach the alveoli is by microaspiration of oropharyngeal secretions.