What is the drug Zonegran used for?
Zonisamide is used with other medications to prevent and control seizures (epilepsy). Zonisamide is a sulfonamide anticonvulsant and a carbonic anhydrase inhibitor. It is unknown how zonisamide works to prevent seizures.
Does zonegran make you sleepy?
SIDE EFFECTS: Dizziness, drowsiness, trouble sleeping, lack of coordination, lightheadedness, loss of appetite, diarrhea, and double vision may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
How much weight can you lose on Zonegran?
The antiepileptic drug zonisamide, at a dosage of 400 mg per day, is associated with enhanced weight loss for obese patients when combined with diet and lifestyle counseling, but the incidence of adverse events is high, according to a study published online Oct. 15 in the Archives of Internal Medicine.
Is Zonegran a mood stabilizer?
Zonegran (zonisamide) is used with other medicines to help control partial seizures. It can’t be used by itself. Prevents seizures and stabilizes mood.
Does zonisamide help with anxiety?
Results from this pilot and open naturalistic study suggest that zonisamide may effectively augment response to anxiolytic medications in patients with treatment refractory anxiety. Larger and controlled studies are warranted to confirm these preliminary findings.
How safe is Zonegran?
Zonegran may cause serious side effects, including: Serious skin rash that can cause death. Serious allergic reactions that may affect different parts of the body. Less sweating and increase in your body temperature (fever).
Can Zonegran cause hair loss?
HAIR LOSS with Zonegran!! Doctor Says There’s No Such Side Effect | Epilepsy Foundation.
Does zonisamide speed up metabolism?
Zonisamide does not induce its own metabolism. Plasma clearance of zonisamide is approximately 0.30–0.35 mL/min/kg in patients not receiving enzyme-inducing antiepilepsy drugs (AEDs).
Does zonegran cause weight gain?
Longitudinal assessment indicated that zonisamide was associated with a significantly slower rate of BMI and weight increases compared with placebo (P = . 01). No patients in the zonisamide group experienced significant weight gain, compared with 33% of placebo-treated patients (P = . 009).
How much Zonisamide is in Zonegran capsules?
Zonisamide is a white powder, pKa = 10.2, and is moderately soluble in water (0.80 mg/mL) and 0.1 N HCl (0.50 mg/mL). The chemical structure is: ZONEGRAN is supplied for oral administration as capsules containing 25 mg, 50 mg or 100 mg zonisamide.
What are the inactive ingredients in Zonegran 25 mg?
Each 25 mg capsule contains the labeled amount of zonisamide plus the following inactive ingredients: microcrystalline cellulose, hydrogenated vegetable oil, sodium lauryl sulfate, gelatin, and titanium dioxide.
Can you take Zonegran with a sleeping pill?
Ask your doctor before taking Zonegran with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety or depression. Other drugs may interact with zonisamide, including prescription and over-the-counter medicines, vitamins, and herbal products.
How is Zonegran classified as an antiseizure drug?
ZONEGRAN® (zonisamide) is an antiseizure drug chemically classified as a sulfonamide and unrelated to other antiseizure agents. The active ingredient is zonisamide, 1,2-benzisoxazole-3- methanesulfonamide. The empirical formula is C8H8N2O3S with a molecular weight of 212.23.