What is clopidogrel bisulfate used to treat?
Clopidogrel is used alone or with aspirin to prevent serious or life-threatening problems with the heart and blood vessels in people who have had a stroke, heart attack, or severe chest pain.
Is there a difference between clopidogrel and clopidogrel bisulfate?
Plavix for oral administration is provided as either pink, round, biconvex, debossed, film-coated tablets containing 97.875 mg of clopidogrel bisulfate which is the molar equivalent of 75 mg of clopidogrel base or pink, oblong, debossed film-coated tablets containing 391.5 mg of clopidogrel bisulfate which is the molar …
How long should you take clopidogrel bisulfate?
The optimal duration of dual antiplatelet therapy is not known; 12 months has been the commonly recommended duration. A recent large trial changed recommendations. Rates of stent thrombosis and death from stroke or heart attack were lower when the two meds were continued for 18 more months.
What are the side effects of taking clopidogrel?
Common side effects of clopidogrel can include:
- headaches or dizziness.
- nausea.
- diarrhoea or constipation.
- indigestion (dyspepsia)
- stomach ache or abdominal pain.
- nosebleeds.
- increased bleeding (your blood taking longer to clot – for example, when you cut yourself), or easy bruising.
Is clopidogrel bisulfate an anticoagulant?
Plavix (clopidogrel bisulfate) and Heparin are anticoagulants (blood thinners) that inhibit aspects of blood clotting and are used to treat patients with acute coronary syndrome, heart attack (myocardial infarction), peripheral vascular disease, and ischemic strokes.
Is Plavix A P2Y12 inhibitor?
Aspirin is an antiplatelet drug that may be used. P2Y12 receptor blockers are another group of antiplatelet drugs. This group of drugs includes: clopidogrel, ticlopidine, ticagrelor, prasugrel, and cangrelor.
Is it safe to take clopidogrel long term?
Take as directed Clopidogrel oral tablet is used for long-term treatment. It comes with serious risks if you don’t take it as prescribed. If you stop taking the drug or don’t take it at all: You increase your risk of heart attack or stroke. These conditions can be fatal.
What happens when you stop taking clopidogrel?
Do not stop taking clopidogrel without talking to your doctor. If you stop taking clopidogrel, your blood will start clotting at the same rate as before you started taking it, usually within 5 days of stopping the medicine. This means you may be at increased risk of serious problems like heart attacks or strokes.
What foods should you avoid while on blood thinners?
5 Things to Avoid If You’re On Blood Thinners
- Leafy greens. Leafy greens like kale, spinach, Brussels sprouts and lettuce contain high amounts of vitamin K.
- Green tea.
- Cranberry juice.
- Grapefruit.
- Alcohol.
How is clopidogrel bisulfate used to treat blood clots?
Clopidogrel bisulfate (Plavix) is an anti-platelet drug, that is, a drug that inhibits the ability of platelets to clump together as part of a blood clot. Clopidogrel prevents blood clots by irreversibly binding to the P2Y12 receptor on platelets, preventing adenosine diphosphate (ADP) from activating platelets.
How is clopidogrel similar to other P2Y12 inhibitors?
It belongs to a class of drugs called P2Y12 inhibitors. Other drugs in this class include ticagrelor (Brilinta) and prasugrel (Effient). Clopidogrel is similar to ticlopidine (Ticlid) in chemical structure and in the way it works.
When was clopidogrel bisulfate approved by the FDA?
Clopidogrel bisulfate is used to reduce the risk of heart attacks and strokes in these patients. Clopidogrel bisulfate was approved by the FDA in 1997. What are the uses for clopidogrel?
When to take clopidogrel before or after PCI?
In patients with STEMI in whom PCI is planned †, experts recommend a loading dose of a P2Y12-receptor antagonist (e.g., clopidogrel, prasugrel, ticagrelor) before or at the time of PCI in conjunction with aspirin therapy. Clopidogrel also has been used in patients with STEMI who are receiving delayed PCI after thrombolytic therapy.