What is a conjunctival intraepithelial neoplasia?
Background: Conjunctival intraepithelial neoplasia (CIN) is the most common tumor of the ocular surface and is a precursor to invasive squamous cell carcinoma. CIN comprises a spectrum of premalignant epithelial neoplasia that usually begins near the limbus and spreads to the cornea.
What is conjunctival neoplasm?
Corneal and conjunctival tumors are malignant cancers that grow on the outer surface of the eye. The most common types of malignant conjunctival tumors are squamous cell carcinoma, malignant melanoma, and lymphoma.
Can you go blind from pterygium?
How serious is it? A pterygium can lead to severe scarring on your cornea, but this is rare. Scarring on the cornea needs to be treated because it can cause vision loss. For minor cases, treatment usually involves eye drops or ointment to treat inflammation.
Does pterygium affect vision?
A pterygium is a growth of tissue in the corner of the eye, which is often triangular in shape. If left untreated, the growth can extend across the pupil obscuring vision or distorting the surface of the eye causing blurred vision.
Is the conjunctival epithelium a carcinoma or a neoplasm?
Conjunctival intraepithelial neoplasia. The conjunctival intraepithelial neoplasia is a squamous neoplasia confined to the conjunctival epithelium that sometimes transgresses the basement membrane but strictly do not have the potential of the metastasize, unlike the invasive squamous carcinoma.
How is the diagnosis of squamous conjunctival neoplasia made?
Diagnosis. The diagnosis of squamous conjunctival neoplasia is typically made by biopsy. Like most squamous epithelial tumors, invasion beneath the epithelium into the substantia propria defines these lesions as carcinoma. When the tumor is contained within the epithelium it does not have access to the lymphatic system (metastatic potential).
What are the risk factors for intrajunctival neoplasia?
Risk factors include exposure to UV light especially in light skinned individuals, human papillomavirus infection (HPV 16 / 18), immunosuppression, tobacco use, vitamin A deficiency, ocular surface injury and exposure to petroleum products ( Ophthalmology 1994;101:360, Ophthalmology 2002;109:542, Cornea 2003;22:687 )
Why does the conjunctival epithelium form a pseudohypopyon?
Epithelial inclusion cyst. The epithelial inclusion cyst could be spontaneous or occur after inflammation, surgery or trauma. It has round form lined by conjunctival epithelium with clear fluid inside. If the fluid has epithelial cells, they can go to the bottom of the cyst and form a pseudohypopyon.