What does perfusion mean on MRI?
Dynamic Susceptibility Contrast-Enhanced MR Perfusion DSC MR perfusion, also known as bolus-tracking MRI or perfusion-weighted imaging, is a technique in which the first pass of a bolus of gadolinium-based contrast agent through brain tissue is monitored by a series of T2- or T2*-weighted MR images.
How is MRI perfusion done?
The common procedure for a DCE-MRI exam is to acquire a regular T1-weighted MRI scan (with no gadolinium), and then gadolinium is injected (usually as an intravenous bolus at a dose of 0.05–0.1 mmol/kg) before further T1-weighted scanning.
What is rCBV MRI?
Aim: Relative cerebral blood volume (rCBV) is a commonly used perfusion magnetic resonance imaging (MRI) technique for the evaluation of tumour grade. Relative cerebral blood flow (rCBF) has been less studied.
What does perfusion mean in medical terms?
Perfusion: The passage of fluid through the circulatory system (blood stream) or lymphatic system to an organ or a tissue, usually referring to the delivery of blood to an area.
Can an MRI take 2 hours?
How long does an MRI take? MRI scans usually take between 45 and 60 minutes, but can sometimes take up to 2 hours. After the test, you may be asked to wait while the pictures are checked to make sure that they are clear and show all of the body part. If not, more pictures may be needed.
What is perfusion analysis?
Perfusion analysis allows imaging of grasping blood-flow abnormalities such as brain infarction, stenosis and occlusion of the main artery in their early stages compared to a plain CT image.
How is rCBV measured?
The relative CBV (rCBV) is calculated by the CBV in the region of interest (e.g. tumour hotspot) divided by the CBV of an internal reference tissue for normalization.
What is time to peak?
Time-to-peak (TTP) is the time at which contrast concentration reaches its maximum. For example, for a particular dynamic susceptibility contrast (DSC) imaging acquisition in which images are acquired every 1.5 seconds, possible TTP values could include 20.0 seconds, 21.5 seconds, 23.0 seconds, etc.
What is required for normal perfusion?
75 to 100 cc/kilo/min. perfusion rate is recommended. Minimal mean arterial pressures (60-70 mmHg) are essential to maintain good function of all organ systems for many hours of perfusion and to avoid disseminated intravascular coagulation by keeping capillary beds open.