What are the three types of von Willebrand disease?
There are three main types of VWD (VWD type 1, VWD type 2, and VWD type 3) each with differing degrees of severity and inheritance patterns. Unlike hemophilia which is characterized by joint bleeding, VWD is typically characterized by mucocutaneous bleeding.
What cleaves von Willebrand?
Human von Willebrand factor (VWF) is cleaved by plasmin in a shear-dependent manner.
What are the three types of von Willebrand Factor deficiency?
Binding with plasma proteins (especially factor VIII) is the main function of von Willebrand factor. The disease is of two forms: Inherited and acquired forms. Inherited forms are of three major types. They are type 1, type 2, and type 3; in which type 2 is sub-divided into 2A, 2B, 2M, 2N.
Which blood component is associated with von Willebrand disease?
Von Willebrand factor is involved in the early stages of blood clotting, and also carries the important clotting protein factor VIII. In people with VWD, the amount of Von Willebrand factor clotting protein in the blood is lower than normal or doesn’t work as it should.
What foods should be avoided with von Willebrand disease?
Food and supplements to avoid
- large glasses of juice.
- soft drinks, energy drinks, and sweetened tea.
- heavy gravies and sauces.
- butter, shortening, or lard.
- full-fat dairy products.
- candy.
- foods containing trans fats, including fried. foods and baked goods (pastries, pizza, pie, cookies, and crackers)
Can you take ibuprofen with von Willebrand disease?
Treatment depends on the type of von Willebrand’s disease you have, how much you bleed, and your risk for heavy bleeding. You may need to: Avoid nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin, ibuprofen (Advil or Motrin, for example), and naproxen (Aleve).
What part of the body does von Willebrand disease affect?
Von Willebrand disease is a lifelong bleeding disorder in which your blood doesn’t clot properly. People with the disease have low levels of von Willebrand factor, a protein that helps blood clot, or the protein doesn’t perform as it should.
At what age is von Willebrand disease diagnosed?
76% of men with VWD had been diagnosed by age 10, but 50% of women with VWD were not diagnosed until after age 12.
Can I take Tylenol with von Willebrand?
To help prevent bleeding episodes, talk with your doctor before taking blood-thinning medications — such as aspirin, ibuprofen (Advil, Motrin IB, others) or naproxen sodium (Aleve). Your doctor might instead recommend pain and fever relievers such as acetaminophen (Tylenol, others). Tell your doctors and dentist.
Can I donate blood with von Willebrand disease?
But I have von Willebrand Disease (VWD), can’t I donate blood? Some blood collection centers will accept donations from people with VWD who have never had a major bleed or required treatment for their VWD. Call first and talk to a donation counselor.
Can von Willebrand cause headaches?
41% of women with VWD reported a diagnosis of migraine headaches compared with 13% of controls. 37% of women with VWD reported a diagnosis of arthritis compared with 15% of controls.
What medications can cause von Willebrand disease?
Which medications should be avoided by patients with pediatric von Willebrand disease (VWD)?
- Over-the-counter medications. Aspirin. Ibuprofen.
- Antiplatelet agents. Dipyridamole. Ticlopidine.
- Antimicrobials. High-dose penicillins. Cephalosporins.
- Cardiovascular medications. Propranolol. Furosemide.
- Others. Caffeine.