What are the functions of satellite cells?
glial cells that surround some neurons in the peripheral nervous system. Their role is not fully understood, but it is thought they provide nutrient support and protection. They may also help to regulate the neuronal environment and be involved in neurotransmission.
What does a satellite glial cell do?
They supply nutrients to the surrounding neurons and also have some structural function. Satellite cells also act as protective, cushioning cells. Additionally, they express a variety of receptors that allow for a range of interactions with neuroactive chemicals.
What do ganglia do?
Ganglia are clusters of nerve cell bodies found throughout the body. They are part of the peripheral nervous system and carry nerve signals to and from the central nervous system.
Why do we have ganglia?
Ganglia provide relay points and intermediary connections between different neurological structures in the body, such as the peripheral and central nervous systems.
Where are satellite cells located in the body?
ganglia
Satellite cells are small, flattened cells found in the ganglia of the peripheral nervous system (ganglion = collection of cell bodies).
Where do satellite cells come from?
In limb and trunk muscles, satellite cells are derived from cells that express both Pax7 and its paralog, Pax3, during embryogenesis, whereas progenitors participating in development of many head muscles do not exhibit Pax3 expression (Epstein et al. 1996; Tajbakhsh et al. 1997; Gros et al. 2005; Relaix et al.
What would happen if satellite cells were destroyed?
In this study, Ramkumar Sambasivan and colleagues at the Pasteur Institute in Paris discovered that when satellite cells were destroyed in mice, other types of cells were unable to repair muscle damage. This study tells us more about how different cell types work together to grow new muscle.
What are glial cell disorders?
Dysfunction in glial cells associates with a variety of brain diseases such as Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, glioblastoma, autism and psychiatric disorders.