What are side effects of probenecid?
Probenecid may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- headache.
- upset stomach.
- vomiting.
- loss of appetite.
- dizziness.
Is probenecid bad for your kidneys?
When you first begin taking probenecid, the amount of uric acid in the kidneys is greatly increased. This may cause kidney stones or other kidney problems in some people.
How long should you take probenecid?
Probenecid is taken twice a day. Most people start with 250 mg (one-half of a 500-mg tablet) two times a day for about one week, then 500 mg (one tablet) two times a day for a few weeks. Your uric acid levels will be tested frequently.
Can you stop taking probenecid?
After you have been taking probenecid for several months, they may stop completely. This medicine will help prevent gout attacks but it will not relieve an attack that has already started. Even if you take another medicine for gout attacks, continue to take this medicine also.
What does probenecid treat?
Probenecid is used to treat gout and gouty arthritis. This medicine reduces the amount of uric acid in your body by causing it to be passed in your urine.
What medications interact with probenecid?
Some products that may interact with this drug include: cancer chemotherapy, baricitinib, dyphylline, ketorolac, methotrexate, pyrazinamide, salicylates (e.g., high-dose aspirin), zidovudine, certain drugs removed from your body by the kidneys (such as ceftazidime/avibactam, dapsone, heparin, fosfomycin).
Which is better allopurinol or probenecid?
Conclusions: In a large cohort study of 38,888 elderly Medicare patients with gout, use of probenecid appears to be associated with a modest decrease in MI, stroke, and admission for heart failure exacerbation compared to allopurinol.
When to tell your doctor about side effects of probenecid?
Inform your doctor if your condition persists or worsens. Nausea, loss of appetite, dizziness, vomiting, headache, sore gums, or frequent urination may occur as your body adjusts to the medicine. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
How many probenecid tablets are in a bottle?
Probenecid Tablets, USP are available containing 500 mg of Probenecid, USP. The tablets are capsule shaped, film-coated yellow, debossed LCI on one side and 1367 on the other side. They are available as follows: NDC 0527-1367-01 bottles of 100 tablets
Are there any drugs that interact with probenecid?
Some products that may interact with this drug include: cancer chemotherapy, ketorolac, dyphylline, methotrexate, pyrazinamide, salicylates (e.g., high-dose aspirin), zidovudine, certain drugs removed from your body by the kidneys (such as ceftazidime/avibactam, dapsone, heparin, fosfomycin).
What are the inactive ingredients in probenecid tablets?
Each tablet for oral administration contains 500 mg of probenecid and the following inactive ingredients: microcrystalline cellulose, sodium lauryl sulfate, sodium starch glycolate, starch (corn), povidone, colloidal silicon dioxide, magnesium stearate, polyvinyl alcohol, titanium dioxide, polyethylene glycol, talc,…