Is septo-optic dysplasia curable?
Although there is no cure for this condition, the treatment is directed toward the specific symptoms in each individual. Children with possible SOD must be kept under careful hormonal follow-up, and, if present, hormone deficiencies should be treated with hormone replacement therapy.
What does septo-optic dysplasia mean?
Septo-optic dysplasia is a disorder of early brain development. Although its signs and symptoms vary, this condition is traditionally defined by three characteristic features: underdevelopment (hypoplasia) of the optic nerves, abnormal formation of structures along the midline of the brain, and pituitary hypoplasia.
Are people with septo-optic dysplasia blind?
Septo-optic dysplasia affects one in 1000 children and boys and girls are affected equally. Symptoms can range from mild visual impairment to complete loss of vision.
At what age is septo-optic dysplasia diagnosed?
It is a rare condition affecting around 1 in every 10,000 births, with boys and girls affected equally. Septo-optic dysplasia is a congenital condition so it is present at birth, although it may not be diagnosed until childhood, or rarely, adolescence.
Is sod a disability?
Septo-optic dysplasia (SOD) is a rare disorder characterized by abnormal development of the optic disk, pituitary deficiencies, and often agenesis (absence) of the septum pellucidum (the part of the brain that separates the anterior horns or the lateral ventricles of the brain).
Can septo-optic dysplasia be detected in pregnancy?
Septo-optic dysplasia can be suspected in utero and can appear isolated but has substantial associated central nervous system anomalies identified on fetal MRI or after birth.
Can optic nerve hypoplasia be cured?
Although no cure for ONH exists, timely intervention may minimize the impact of vision loss and generally improve development in these children. An underdeveloped optic nerve is a congenital problem, leading to eyesight deterioration.
Can septo-optic dysplasia be seen on ultrasound?
All imaging modalities that can visualize the septum pellucidum (ultrasound, CT and MRI) will detect its absence in septo-optic dysplasia.
Can septo optic dysplasia be seen on ultrasound?
What is the function of septum pellucidum?
The septum pellucidum acts as a partition between a portion of the lateral ventricles, forming part of the walls of the anterior region of the lateral ventricles.
Can optic nerves be repaired?
In the case of the optic nerve, it is a person’s vision that is lost or impaired. The optic nerve is part of the central nervous system and cannot regenerate or repair itself because of natural inhibitors in the body that block its re-growth.
What do you need to know about septo optic dysplasia?
Septo-optic dysplasia (SOD) is a rare disorder characterized by abnormal development of the optic disk, pituitary deficiencies, and often agenesis (absence) of the septum pellucidum (the part of the brain that separates the anterior horns or the lateral ventricles of the brain).
How is septo-optic dysplasia related to pituitary deficiencies?
Related Information. Septo-optic dysplasia (SOD) is a rare disorder characterized by abnormal development of the optic disk, pituitary deficiencies, and often agenesis (absence) of the septum pellucidum (the part of the brain that separates the anterior horns or the lateral ventricles of the brain).
When is a diagnosis of optic dysplasia made?
A diagnosis of SOD is made when at least two of the following triad are present: optic nerve underdevelopment; pituitary hormone abnormalities; or mid-line brain abnormalities. Diagnosis is usually made at birth or during childhood, and a clinical diagnosis can be confirmed by MRI scans. There is no cure for SOD.
When did Georges de Morsier diagnose septo optic dysplasia?
Two or more of these features need to be present for a clinical diagnosis — only 30% of patients have all three. French-Swiss doctor Georges de Morsier first recognized the relation of a rudimentary or absent septum pellucidum with hypoplasia of the optic nerves and chiasm in 1956.