Is erdheim Chester disease painful?
People with Erdheim-Chester disease often have bone pain, especially in the lower legs and upper arms, due to an abnormal increase in bone density (osteosclerosis).
Is erdheim Chester disease an autoimmune disease?
Erdheim-Chester disease (ECD) is an infrequent, autoimmune disorder that is not Langerhans histiocytosis and is characterized by bilateral sclerosis of the diametaphyseal medullary regions of the long bones and possible multiorgan involvement.
What is erdheim Chester syndrome?
Erdheim-Chester disease (ECD) is a rare multisystem disorder of adulthood. It is characterized by excessive production and accumulation of histiocytes within multiple tissues and organs. Histiocytes are large phagocytic cells (macrophages) that normally play a role in responding to infection and injury.
What is the treatment for erdheim Chester?
The U.S. Food and Drug Administration today expanded the approval of Zelboraf (vemurafenib) to include the treatment of certain adult patients with Erdheim-Chester Disease (ECD), a rare cancer of the blood. Zelboraf is indicated to treat patients whose cancer cells have a specific genetic mutation known as BRAF V600.
What is the rarest disease in the world?
Five rare diseases you never knew existed
- Stoneman Syndrome. Frequency: one in two million people.
- Alice In Wonderland Syndrome (AIWS) Frequency: currently unknown.
- Hutchinson-Gilford Progeria Syndrome (HGPS) Frequency: one in four million.
- Alkaptonuria.
- Chronic Focal Encephalitis (Rasmussen’s Encephalitis)
How do you test for erdheim Chester disease?
The disease is diagnosed based on the symptoms, biopsies of involved tissue examined under a microscope (pathology), and specialized tests that may include blood tests and imaging studies such as X-rays , CT scans , MRIs , and bone scans. There is no cure or standard treatment for ECD.
What is the laughing death disease?
Kuru (disease)
| Kuru | |
|---|---|
| Specialty | Neuropathology |
| Symptoms | Body tremors, random outbursts of laughter, gradual loss of coordination |
| Complications | Infection and pneumonia during the terminal stage. |
| Usual onset | Often takes years or even decades for symptoms to appear after exposure |