Is CMV a DNA virus?
Human cytomegalovirus (HCMV) is classified as a DNA herpesvirus. A recent study showed that the HCMV virion contains not only DNA, but also four species of mRNA, indicating that this virus is more complex than previously believed.
Is CMV DNA or RNA?
Cytomegalovirus (CMV) is a double-stranded DNA virus and is a member of the Herpesviridae family.
Is CMV dsDNA?
T-cells are essential for control of double stranded DNA (dsDNA) viruses including cytomegalovirus (CMV), adenovirus (ADV), human herpesvirus 6 (HHV6) and Epstein-Barr virus (EBV)6, 7.
What is CMV DNA?
Quantitative CMV DNA PCR testing provides a “viral load” value useful for. monitoring antiviral therapy and possible identifying patients at risk for CMV disease. Clinical Significance: Human Cytomegalovirus (CMV) is a member of the Herpes Virus.
What is CMV gene?
CMV is an ancient herpesvirus that has co-evolved with its host over millions of years. The 236 kbp genome encodes at least 165 genes, four non-coding RNAs and 14 miRNAs. Of the protein-coding genes, 43–44 are core replication genes common to all herpesviruses, while ~30 are unique to betaherpesviruses.
Where does CMV virus come from?
People with CMV may pass the virus in body fluids, such as saliva, urine, blood, tears, semen, and breast milk. CMV is spread from an infected person in the following ways: From direct contact with saliva or urine, especially from babies and young children. Through sexual contact.
What is CMV DNA test?
CMV DNA viral load testing is an important aid for assessing risk of disease, diagnosing disease, and monitoring response to therapy. The interpretation of CMV DNA viral load values can be complex, and numerous virus and host factors should be considered when assessing the risk of CMV disease.
How is CMV detected?
The standard laboratory test for diagnosing congenital CMV infection is polymerase chain reaction (PCR) on saliva, with urine usually collected and tested for confirmation. The reason for the confirmatory test on urine is that most CMV seropositive mothers shed CMV in their breast milk.
How common is the CMV virus?
Cytomegalovirus (CMV) is a virus related to the herpes virus. It is so common that almost all adults in developing countries and 50% to 85% of adults in the United States have been infected. Usually CMV is a mild disease that does not cause any serious problems in healthy children and adults.