How long does someone with osteogenesis imperfecta live?
The median survival time in the OI cohort was 72.4 years for males (compared to 81.5 years in the reference population) and 77.4 for females (compared to 84.5 in the reference population).
How long can you live with OI?
Life expectancy for males with OI was 9.5 years shorter than that for the general population (72.4 years vs 81.9 years), and for females, was 7.1 years shorter than that for the general population (77.4 years vs 84.5 years).
Is osteogenesis imperfecta life long?
A child born with OI may have soft bones that break (fracture) easily, bones that are not formed normally, and other problems. Signs and symptoms may range from mild to severe. The main goal of treatment is to prevent deformities and fractures. OI is a lifelong condition.
What is the quality of life like for someone with osteogenesis imperfecta?
In this large-sample study, we demonstrated that osteogenesis imperfecta (OI) significantly impaired the quality of life (QoL) in children. Moderate/severe OI patients had worse QoL scores than patients with mild OI. Furthermore, the QoL for OI patients was correlated with the presence of pathogenic gene mutations.
Can you grow out of osteogenesis imperfecta?
OI is a childhood disorder; people grow out of it by their teens. FACT: OI is a genetic disorder that is present throughout a person’s lifetime. Many people with OI have fewer fractures after puberty when growth stops, but the genetic difference remains.
Can you grow out of brittle bone disease?
There is no cure for brittle bone disease, but treatment can relieve symptoms, prevent breakage of bones, and maximize movement. Severe forms of the disease can affect the shape of the rib cage and spine, which can lead to life-threatening breathing problems.
Does osteogenesis imperfecta get worse with age?
In type 3 OI, your child’s body produces enough collagen but it’s poor quality. Your child’s bones can even begin to break before birth. Bone deformities are common and may get worse as your child gets older.
How does OI affect the lungs?
OI Affects the Lungs The primary respiratory problem affecting people with OI is loss of lung capacity. Other problems include ineffective cough, poor secretion clearance, airway diseases such as asthma, sleep apnea, and low oxygen. These problems affect people of all ages and all types of OI.
Can unborn baby bones break?
A baby’s bones are different from an adult’s bones. Babies are born with more bones than an adult; over time, some of them fuse together. At birth, however, they are softer and more fragile than an adult’s bones. While any bone can break during birth, the most common breaks include clavicles or collarbones.
Can people live with OI?
Babies born with mild types of OI can live healthy lives into adulthood. Osteogenesis imperfecta treatment focuses on increasing bone strength and improving quality of life.