Which condition can cause rhabdomyolysis?
Although rhabdomyolysis is most often caused by direct traumatic injury, the condition can also be the result of drugs, toxins, infections, muscle ischemia, electrolyte and metabolic disorders, genetic disorders, exertion or prolonged bed rest, and temperature-induced states such as neuroleptic malignant syndrome (NMS) …
Why is rhabdomyolysis a serious condition?
Rhabdomyolysis is a serious syndrome due to a direct or indirect muscle injury. It results from the death of muscle fibers and release of their contents into the bloodstream. This can lead to serious complications such as renal (kidney) failure. This means the kidneys cannot remove waste and concentrated urine.
What are the complications of rhabdomyolysis?
Complications of rhabdomyolysis include the following:
- Electrolyte abnormalities.
- Hypoalbuminemia.
- Hyperuricemia.
- Compartment syndrome.
- Acute kidney injury (AKI) and renal failure.
- Disseminated intravascular coagulation (DIC, a late complication)
Can dehydration cause rhabdomyolysis?
Dehydration doesn’t cause rhabdo but dehydration can make it worse. Dehydration impairs the body’s ability to get rid of the muscle proteins and electrolytes that are released into the body when the muscle is damaged.
What does muscle death feel like?
Muscle spasm in the affected area. Numbness and tingling in an arm or leg. Paleness (pallor) of the skin of the arm or leg. Muscle weakness of an arm or leg, possibly to the grade of paralysis.
Does rhabdomyolysis affect the heart?
Rhabdomyolysis may cause severe damage to the human body because of acute renal failure, fatal heart rhythm disturbances, hypovolemic shock, disturbances of electrolyte balance, metabolic acidosis, hyperthermia, disseminated intravascular coagulation, etc. Drugs and toxins are the most common factors for the disease.
How does rhabdomyolysis cause kidney damage?
When muscle is damaged, a protein called myoglobin is released into the bloodstream. It is then filtered out of the body by the kidneys. Myoglobin breaks down into substances that can damage kidney cells.
How does dehydration cause rhabdomyolysis?
What labs indicate rhabdomyolysis?
Blood tests include a complete blood count (CBC), a metabolic panel, muscle enzymes, and urinalysis. The diagnosis of rhabdomyolysis is confirmed by detecting elevated muscle enzymes in blood, which include creatine phosphokinase (CPK), SGOT, SGPT, and LDH .