Which antipsychotics are phenothiazine?
Examples of phenothiazine antipsychotics are:
- prochlorperazine (Compazine, Compro, Procomp),
- chlorpromazine (Promapar, Thorazine),
- fluphenazine (Permitil, Prolixin),
- perphenazine,
- trifluoperazine (Stelazine),
- thioridazine (Mellaril), and.
- mesoridazine (no longer available in the United States).
Is haloperidol a phenothiazine?
Haloperidol is a typical butyrophenone type antipsychotic that exhibits high affinity dopamine D2 receptor antagonism and slow receptor dissociation kinetics. It has effects similar to the phenothiazines.
What is phenothiazine used for?
Phenothiazines are used to treat serious mental and emotional disorders, including schizophrenia and other psychotic disorders. Some are used also to control agitation in certain patients, severe nausea and vomiting, severe hiccups, and moderate to severe pain in some hospitalized patients.
Which antipsychotic compound is aliphatic side chain to phenothiazine?
Cyamemazine (Tercian), also known as cyamepromazine, is a typical antipsychotic drug of the phenothiazine class used primarily in the treatment of schizophrenia and psychosis-associated anxiety.
What is the best known phenothiazine?
Among the most widely used phenothiazines are chlorpromazine (marketed under Thorazine and other trade names), thioridazine (Mellaril), and trifluoperazine (Stelazine).
Is Xanax a phenothiazine?
Compazine is used to treat psychotic disorders such as schizophrenia. Compazine is also used to control severe nausea and vomiting. Xanax is also used to treat panic attacks. Compazine is a phenothiazine anti-psychotic and Xanax is a benzodiazepine.
Which of the following is a prodrug?
Examples of prodrugs that exist naturally or were produced unintentionally during drug development include aspirin, psilocybin, parathion, irinotecan, codeine, heroin, L-dopa, and various antiviral nucleosides.
Is phenothiazine used for moderate sedation?
Anesthesia and Analgesia* Phenothiazine tranquilizers, such as acetylpromazine, have been commonly used both alone for sedation as well as in combination with dissociative agents, such as ketamine, for general anesthesia of rabbits (7, 8, 10–12).
What is the aliphatic compound of phenothiazine?
Phenothiazine antipsychotics are classified into three groups that differ with respect to the substituent on nitrogen: the aliphatic compounds (bearing acyclic groups), the “piperidines” (bearing piperidine-derived groups), and the piperazine (bearing piperazine-derived substituents).
How many rings does phenothiazine have?
Structure and synthesis The central C4SN ring is folded in phenothiazines. The compound was originally prepared by Bernthsen in 1883 via the reaction of diphenylamine with sulfur, but more recent syntheses rely on the cyclization of 2-substituted diphenyl sulfides.