What is the mode of action of acyclovir?
Mechanism of Action: Acyclovir is converted to its triphosphate form, acyclovir triphosphate (ACV-TP), which competitively inhibits viral DNA polymerase, incorporates into and terminates the growing viral DNA chain, and inactivates the viral DNA polymerase.
What are three modes of action for antiviral drugs?
The possible modes of action of anti-viral agents would include being able to …
- Inactivate extracellular virus particles.
- Prevent viral attachment and/or entry.
- Prevent replication of the viral genome.
- Prevent synthesis of specific viral protein(s).
- Prevent assembly or release of new infectious virions.
What is the mode of action for antiviral drugs?
An analysis of the action mechanism of known antiviral drugs concluded that they can increase the cell’s resistance to a virus (interferons), suppress the virus adsorption in the cell or its diffusion into the cell and its deproteinisation process in the cell (amantadine) along with antimetabolites that causes the …
How does the drug acyclovir work?
Acyclovir works by lowering the ability of the herpes virus to multiply in your body. This treats the symptoms of your infection. However, this drug doesn’t cure herpes infections. Herpes infections include cold sores, chickenpox, shingles, or genital herpes.
What are the indications for acyclovir?
ZOVIRAX® (acyclovir) is indicated for the following conditions: The treatment of initial episodes of herpes genitalis. The suppression of unusually frequent recurrences of herpes genitalis (6 or more episodes per year). The acute treatment of herpes zoster (shingles) and varicella (chickenpox).
What is the target of acyclovir?
Acyclovir is an antiviral drug that has activity against herpes simplex virus types 1 (HSV-1), 2 (HSV-2), and varicella-zoster virus (VZV). Acyclovir works in several different ways to prevent these viruses from replicating. Activity against HSV is greater than activity against VZV.
What do antiviral drugs mainly target?
Most antivirals target specific viruses, while a broad-spectrum antiviral is effective against a wide range of viruses. Unlike most antibiotics, antiviral drugs do not destroy their target pathogen; instead they inhibit its development.
Why are antiviral drugs difficult?
Moreover, antivirals have a limited number of possible shapes. That’s because, to block a virus’s actions, they must fit into viral proteins as decoys. The biggest challenge, says Seley-Radtke, is to ensure that the drugs don’t hurt the human hosts as well.
Is acyclovir an antiretroviral drug?
Acyclovir is an antiviral prescription medicine approved by the U.S. Food and Drug Administration (FDA) to: Treat and/or prevent the recurrence of certain types of herpes simplex virus (HSV) infections, including genital herpes.
How does acyclovir act as an antiviral?
Acyclovir is in a class of antiviral medications called synthetic nucleoside analogues. It works by stopping the spread of the herpes virus in the body. Acyclovir will not cure genital herpes and may not stop the spread of genital herpes to other people.
Which of the following is an effect of antiviral drugs?
Antiviral drugs can ease symptoms and shorten how long you are sick with viral infections like the flu and Ebola. They can rid your body of these viruses. Viral infections like HIV, hepatitis and herpes are chronic. Antivirals can’t get rid of the virus, which stays in your body.
What are the side effects of antiviral drugs?
What are the potential side effects of antivirals?
- Cough.
- Dry mouth.
- Diarrhea.
- Dizziness.
- Fatigue.
- Headaches.
- Insomnia.
- Joint pain or muscle pain.