What is the DCCT trial?
The Diabetes Control and Complications Trial (DCCT) is a multicenter, randomized, clinical study designed to determine whether an intensive treatment regimen directed at maintaining blood glucose concentrations as close to normal as possible will affect the appearance or progression of early vascular complications in …
What were the results of the DCCT and other similar trials?
RESULTS. The DCCT followed >99% of the cohort for a mean of 6.5 years and demonstrated a 35–76% reduction in the early stages of microvascular disease with INT, with a median HbA1c of 7%, compared with CONV, with a median HbA1c of 9%.
What does DCCT mean?
Diabetes Control and Complications Trial
DCCT
| Acronym | Definition |
|---|---|
| DCCT | Diabetes Control and Complications Trial (NIDDK) |
| DCCT | Distributed Computing and Communications Technology |
| DCCT | Dreams Can Come True (Los Angeles, CA) |
| DCCT | Dismounted Close Combat Training |
What year was the DCCT trial?
RESEARCH DESIGN AND METHODS The DCCT (1982–1993) was a controlled clinical trial in 1,441 subjects with T1DM comparing intensive therapy (INT), aimed at achieving levels of glycemia as close to the nondiabetic range as safely possible, with conventional therapy (CON), which aimed to maintain safe asymptomatic glucose …
What is HbA1c IFCC?
The old, percentage way of reporting HbA1c values is known as the DCCT (Diabetes Control and Complications Trial) units. The new mmols/mol values are known as the IFCC (International Federation of Clinical Chemistry) units.
When was the DCCT published?
Following the feasibility study, the full relationship between mean blood glucose levels (derived from the seven-point daily blood glucose profiles) and HbA1c levels observed in the DCCT was published in 2002 and has been, until recently,62 the best guide to compare the two measurements,63 notwithstanding the different …
What is the normal HbA1c level IFCC Standardised?
Normal ranges and values Since 1st June 2009, HbA1c results in the UK have been standardised to the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) which will allow global comparison of results, with the equivalent normal non-diabetic range of IFCC-HbA1c being 20-42 mmol/mol.
What is a DCCT range?
The DCCT (Dismounted Close Combat Trainer) is a computerised version of a live firing range. It allows troops to better hone their skills without the added pressure of temperature and weather. They will subsequently move on to the live firing ranges outdoors.
What does DCCT aligned mean?
HbA1c results in the UK have usually been aligned to the assay used in the Diabetes Control and Complications Trial (DCCT), expressed as a percentage (DCCT-HbA1c) – non-diabetic ‘normal’ range being 4-6%.
What does HbA1c?
A hemoglobin A1c (HbA1c) test measures the amount of blood sugar (glucose) attached to hemoglobin. Hemoglobin is the part of your red blood cells that carries oxygen from your lungs to the rest of your body.
What does HbA1c Levl IFCC Standardised mean?
HbA1c is your average blood glucose (sugar) levels for the last two to three months. If you have diabetes, an ideal HbA1c level is 48mmol/mol (6.5%) or below. If you’re at risk of developing type 2 diabetes, your target HbA1c level should be below 42mmol/mol (6%).