What is high MPV in blood?
A high MPV means that your platelets are larger than average. This is sometimes a sign that you’re producing too many platelets. Platelets are produced in the bone marrow and released into the bloodstream. Larger platelets are usually young and more recently released from the bone marrow.
What does high MPV and normal platelet count mean?
High platelet count along with high MPV can occur when the bone marrow produces too many platelets, typically due to a genetic mutation or cancer. Normal platelet count along with high MPV suggests conditions such as hyperthyroidism or chronic myelogenous leukemia (CML)—a type of cancer.
How is MPV calculated in blood test?
The most commonly available derived parameter is the mean platelet volume (MPV), calculated by dividing the plateletcrit (PCT) by the total number of platelets. This is analogous to the calculation for the mean red cell volume (MCV), in which the hematocrit is divided by the total red cell count.
Can anemia cause high MPV?
Seven patients had high MPV and high platelet count: causes included myeloproliferative disorders, inflammation, iron deficiency, and splenectomy, 25 patients had high platelet counts and normal MPV: the causes were inflammation, infection, sickle cell anemia, iron deficiency, or chronic myelogenous leukemia.
When should you be concerned about high MPV?
If your platelet count is within that range, that may show that you have an average amount of platelets. However, if it falls under 150,000 or above 450,000, that could suggest that you have a health problem.
What should I do if my platelet count is high?
Your doctor might recommend that you take daily, low-dose aspirin to help thin your blood if you’re at risk of blood clots. Don’t take aspirin without checking with your doctor. You might need to take drugs or have procedures to lower your platelet counts if you: Have a history of blood clots and bleeding.
How high is too high for platelets?
In general, a platelet count more than 450,000 cells per microliter is considered elevated; this is known as thrombocytosis.
What is the most common cause of high platelet count?
Infection. In both children and adults, infections are the most common cause of an elevated platelet count. 1 This elevation can be extreme, with platelet counts greater than 1 million cells per microliter.
Can stress cause high platelets?
Stressful life events and anxiety usually cause an increase in platelet volume and activity through various mechanisms. Mean platelet volume (MPV), which is indicative of platelet size, is accepted as an indication of platelet activity.