What is drug idiosyncrasy?
“Drug idiosyncrasy” refers to untoward reactions to drugs that occur in a small fraction of patients and have no obvious relationship to dose or duration of therapy. The liver is a frequent target for toxicity.
What is idiosyncrasy and allergy with example?
Idiosyncratic reactions are unpredictable and not explained by the pharmacologic properties of the drug. An example is the individual with infectious mononucleosis who develops a rash when given ampicillin.
What is the difference between idiosyncrasy and hypersensitivity?
hypersensitivity to a substance, without connection to pharmacological toxicity. Idiosyncrasy stresses here the fact that other individuals would react differently, or not at all and that the reaction is an individual one, based on a specific condition of the one who suffers from it (1).
What is an example of an idiosyncrasy?
The definition of an idiosyncrasy is an unusual behavior, mannerism or reaction of a person or group of people. An example of idiosyncrasy is someone being allergic to air. A behavior or way of thinking that is characteristic of a person.
What are synonyms for idiosyncrasy?
synonyms for idiosyncrasy
- eccentricity.
- mannerism.
- peculiarity.
- trait.
- affectation.
- bit.
- characteristic.
- distinction.
What is allergy in pharmacology?
A drug allergy is the abnormal reaction of your immune system to a medication. Any medication — over-the-counter, prescription or herbal — is capable of inducing a drug allergy. However, a drug allergy is more likely with certain medications. The most common signs and symptoms of drug allergy are hives, rash or fever.
What’s a synonym for idiosyncrasy?
eccentricity, mannerism, peculiarity, trait, affectation, bit, characteristic, distinction, feature, habit, singularity, trick.
Which is not an allergy or an idiosyncratic drug reaction?
Idiosyncrasy is not a drug allergy, but both are forms of adverse drug reaction Idiosyncratic drug reactions are unrelated to the dose of the drug Common lifethreatening idiosyncratic drug reactions include DRESS syndrome, toxic epidermal necrolysis and Stevens-Johnson syndrome Pharmacological definition of idiosyncrasy
What does drug idiosyncrasy mean in medical terms?
“Drug idiosyncrasy” refers to untoward reactions to drugs that occur in a small fraction of patients and have no obvious relationship to dose or duration of therapy. The liver is a frequent target for toxicity.
Is it possible to predict an idiosyncratic reaction?
To be clear, an idiosyncratic reaction is abnormal in nature and is therefore not possible to predict who may develop one, when, or what specific form it will take ahead of time. While the good news is that idiosyncratic reactions aren’t all that common, the bad news is that when they do occur, many tend to be life-threatening in nature.
Why is the liver a common site of idiosyncratic reactions?
Most commonly, this results in the death of liver cells, causing jaundice, failure, or even death. The reason the liver is a common site of idiosyncratic reactions is because it is the place where drugs are converted into an active form, prior to entering your general circulation.