What is an overdose of duloxetine?
Duloxetine overdose symptoms can include somnolence, coma, serotonin syndrome, seizures, syncope, tachycardia, hypotension, hypertension and vomiting (2).
How many mg of Cymbalta is too much?
Typical maintenance dosage: Total daily dose of 40 mg (given as 20-mg doses twice daily) or 60 mg (given either once daily or as 30-mg doses twice daily). Maximum dosage: 120 mg per day.
Is Cymbalta FDA approved in kids?
Increased risk of suicidal thinking and behavior in children, adolescents, and young adults taking antidepressants for major depressive disorder (MDD) and other psychiatric disorders. Cymbalta is not approved for use in pediatric patients (5.1).
Is 120mg of Cymbalta safe?
Results from this study suggest that rapid dose escalation of duloxetine (60 mg/day –> 90 mg/day –> 120 mg/day) is safe and tolerable. Despite weekly escalation, the majority of adverse events were mild and transient and occurred in the first week of duloxetine dosing (at 60 mg once daily).
Can an overdose of Cymbalta be fatal?
Fatal overdoses of duloxetine have been reported with as little as 1,000 milligrams. Overdoses generally manifest with sleepiness, coma, serotonin syndrome, seizures, tachycardia, hyper or hypotension, and vomiting. Treatment should be supportive.
Can Cymbalta cause death?
Serotonin syndrome/neuroleptic malignant syndrome (NMS): This is a rare side effect of the group of medications like Cymbalta. It is life-threatening and can lead to death. It can cause serious changes in how your brain, muscles, digestive system and nervous system work.
Can a 12 year old take Cymbalta?
Duloxetine is not approved for use by anyone younger than 7 years old.
Does Cymbalta have a black box warning?
Black Box Warning for Suicide Risk Cymbalta carries a black box warning stating that antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents and young adults in short-term studies.
How much Cymbalta is toxic?
Fatal overdoses of duloxetine have been reported with as little as 1,000 milligrams. Overdoses generally manifest with sleepiness, coma, serotonin syndrome, seizures, tachycardia, hyper or hypotension, and vomiting. Treatment should be supportive. Activated charcoal may be useful in reducing absorption.
How many mg of Cymbalta should a 7 year old take?
Children and Adolescents (7 to 17 years of age) — Initiate CYMBALTA at a dose of 30 mg once daily for 2 weeks before considering an increase to 60 mg. The recommended dose range is 30 to 60 mg once daily.
What are the side effects of Cymbalta for children?
Common possible side effects in children and adolescents who take Cymbalta include: 1 nausea 2 decreased weight 3 dizziness
Is there a risk of overdosing on Cymbalta?
When users take it as prescribed, there is no risk of Cymbalta overdose. However, when too much Duloxetine is taken, or users mix it with contraindicated substances, overdosing is possible. Users should understand the facts of overdose on Cymbalta and how to avoid one.
When to increase the dose of Cymbalta in the elderly?
Elderly — Initiate Cymbalta at a dose of 30 mg once daily for 2 weeks before considering an increase to the target dose of 60 mg. Thereafter, patients may benefit from doses above 60 mg once daily. If a decision is made to increase the dose beyond 60 mg once daily, increase dose in increments of 30 mg once daily.