What is 2-Pam chloride used for?
Pralidoxime (2-pyridine aldoxime methyl chloride) or 2-PAM, usually as the chloride or iodide salts, belongs to a family of compounds called oximes that bind to organophosphate-inactivated acetylcholinesterase. It is used to treat organophosphate poisoning in conjunction with atropine and either diazepam or midazolam.
How do you give 2-Pam?
MILD SYMPTOMS
- For treatment of mild symptoms, administer a 600 mg (2 mL) intramuscular dose of PROTOPAM (pralidoxime chloride) .
- If, after 15 minutes, mild symptoms persist, then administer a second 600 mg (2 mL) intramuscular dose of PROTOPAM (pralidoxime chloride) .
When do you use 2-Pam?
Pralidoxime ( 2-PAM CL ) is most effective if administered immediately after the poisoning but not before Atropine, especially for severe exposures. If available Diazepam ( Valium ) may be cautiously given, under direct medical control, if convulsions are not controlled.
What is atropine injection used for?
Atropine Injection is given before anaesthesia to decrease mucus secretions, such as saliva. During anaesthesia and surgery, atropine is used to help keep the heart beat normal. Atropine sulfate monohydrate is also used to block or reverse the adverse effects caused by some medicines and certain type of pesticides.
What is OP poisoning?
Organophosphate poisoning is poisoning due to organophosphates (OPs). Organophosphates are used as insecticides, medications, and nerve agents. Symptoms include increased saliva and tear production, diarrhea, vomiting, small pupils, sweating, muscle tremors, and confusion.
When do you stop Pam in OP poisoning?
Pralidoxime (2-PAM, Protopam) Current recommendation is administration within 48 h of OP poisoning. Because it does not significantly relieve depression of the respiratory center or decrease muscarinic effects of AChE poisoning, administer atropine concomitantly to block these effects of OP poisoning.
What is OPC poisoning?
Is atropine a painkiller?
Ophthalmic atropine is used before eye examinations to dilate (open) the pupil, the black part of the eye through which you see. It is also used to relieve pain caused by swelling and inflammation of the eye.
What happens if you swallow organophosphate?
Within several weeks to several days after ingesting a small amount, the person may experience lung scarring and the failure of multiple organs. This includes heart failure, respiratory failure, kidney failure, and liver failure.