What happens when the medial temporal lobe is damaged?
Medial temporal lobe (MTL) damage in humans is typically thought to produce a circumscribed impairment in the acquisition of new enduring memories, but recent reports have documented deficits even in short-term maintenance.
What is the role of medial temporal lobe in memory?
The medial temporal lobe (MTL) includes the hippocampus, amygdala and parahippocampal regions, and is crucial for episodic and spatial memory. MTL memory function consists of distinct processes such as encoding, consolidation and retrieval. After encoding, memory traces are stabilized by consolidation.
What does the medial temporal lobe control?
The medial temporal lobe includes a system of anatomically related structures that are essential for declarative memory (conscious memory for facts and events).
Does amnesia affect the temporal lobe?
His lateral temporal damage also may have contributed to his extensive retrograde amnesia. The findings illuminate the anatomical relationship between memory, perception, and semantic knowledge. The medial temporal lobe has been associated with memory function for more than a century (1⇓–3).
What memory is in the temporal lobe?
The temporal lobe consists of structures that are vital for declarative or long-term memory. Declarative (denotative) or explicit memory is conscious memory divided into semantic memory (facts) and episodic memory (events).
What causes temporal lobe amnesia?
These structures include the thalamus, which lies deep within the center of your brain, and the hippocampal formations, which are situated within the temporal lobes of your brain. Amnesia caused by brain injury or damage is known as neurological amnesia. Possible causes of neurological amnesia include: Stroke.
What lobe causes amnesia?
Case studies also show that amnesia is typically associated with damage to the medial temporal lobe. In addition, specific areas of the hippocampus (the CA1 region) are involved with memory. Research has also shown that when areas of the diencephalon are damaged, amnesia can occur.
Can TLE go away?
What is the outlook? Two out of 3 people with temporal lobe epilepsy achieve good seizure control with seizure medication. Seizures may also go away in some children with TLE. A good outcome is most often seen in people with normal MRI scans.
Can TLE be treated?
TLE is treated with medications, resective surgery, and vagus nerve stimulation. Epilepsy surgery should be considered in all patients with refractory partial epilepsy.