What does Quantec stand for?
Quantitative Analysis of Normal Tissue Effects in the Clinic (QUANTEC)
What td5 5?
[7] The tolerance dose TD5/5 represents the radiation dose that would result in 5% risk of severe complications within 5 years after irradiation and TD50/5 represents the dose that would result in 50% probability of developing severe complications within 5 years after irradiation.
What is tumor control probability?
The tumour control probability (TCP) is a formalism derived to compare various treatment regimens of radiation therapy, defined as the probability that given a prescribed dose of radiation, a tumour has been eradicated or controlled.
What is normal tissue complication probability?
Definition. The probability that a given dose of radiation will cause an organ or structure to experience complications considering the specific biological cells of the organ or structure. The NTCP is used in treatment planning as a tool to differentiate among treatment plans.
What is Quantec radiotherapy?
The recommendations, known as the Quantitative Analysis of Normal Tissue Effects in the Clinic (QUANTEC), address a fundamental challenge in radiation oncology treatment: the competing needs to limit normal tissue damage and to deliver a therapeutic dose to the cancer.
What is Ntcp in radiotherapy?
In radiotherapy, Tumor Control Probability (TCP) is a parameter used to calculate the percentage of tumor killing, while its effect on normal tissue damage describe by Normal Tissue Complication Probability (NTCP).
What is the main purpose and application of NTCP model?
The NTCP is used in treatment planning as a tool to differentiate among treatment plans. A dose-dependent mathematical model to gauge the probability of dose-induced complications in noncancerous tissue.
What is Ntcp model?
Abstract. Mathematical models of normal tissue complication probability (NTCP) able to robustly predict radiation-induced morbidities (RIM) play an essential role in the identification of a personalized optimal plan, and represent the key to maximizing the benefits of technological advances in radiation therapy (RT).
What is a Ntcp model?
What is TCP and NTCP?