What class of drug is Zoladex?
Zoladex is classified as a luteinizing hormone releasing hormone (LHRH) agonist. LHRH agonists work by telling the pituitary gland located in the brain to stop producing luteinizing hormone, which (in men) stimulates the testicles to release testosterone and (in women) stimulates the ovaries to release estrogen.
What is goserelin injection used for?
Goserelin implant is used in combination with radiation therapy and other medications to treat localized prostate cancer and is used alone to treat the symptoms associated with advanced prostate cancer. It is also used to treat advanced breast cancer in certain women.
What is the function of Zoladex?
Zoladex contains a medicine called goserelin. This belongs to a group of medicines called ‘LHRH analogues’. In men, Zoladex is used to treat prostate cancer. It works by reducing the amount of ‘testosterone’ (a hormone) that is produced by your body.
Is goserelin cytotoxic?
The results from these studies provide evidence that goserelin, alone or in combination with tamoxifen, is at least as effective as cytotoxic chemotherapy in patients with hormone receptor-positive tumours and is effective when used after adjuvant chemotherapy.
Is Zoladex the same as goserelin?
Zoladex is the trade name for goserelin. In some cases, health care professionals may use the trade name zoladex when referring to the generic drug name goserelin. Drug type: Goserelin is a hormone therapy. It is classified as an “LHRH agonist.” (For more detail, see “How this drug works” section below).
What is the difference between Zoladex and goserelin?
Goserelin is the generic (non‑branded) name of the drug. Its current brand name is Zoladex. It can also be used to try to preserve fertility during chemotherapy.
Why is goserelin given?
Goserelin is used to treat some people with primary breast cancer. It may also be used to treat people with secondary breast cancer. It’ll only be given if you are premenopausal and your breast cancer is ER+.
What is a goserelin implant?
Goserelin is a man-made form of a hormone that regulates many processes in the body. Goserelin overstimulates the body’s own production of certain hormones, which causes that production to shut down temporarily. Goserelin implant is used in men to treat symptoms of prostate cancer.
What is goserelin acetate implant?
Goserelin acetate implant is a newly approved depot formulation of a luteinizing hormone-releasing hormone (LHRH) agonist indicated for palliation of advanced prostate cancer. LHRH superagonists suppress gonadotropin release from the pituitary gland by causing down-regulation of receptors.
What is the difference between Lupron and Zoladex?
Zoladex contains the active drug goserelin. Lupron Depot contains the active drug leuprolide. Although they contain different active drugs, Zoladex and Lupron Depot work in the same way. They both block production of certain hormones, including estrogen and testosterone.
What should be considered before administering goserelin injection?
Before starting goserelin treatment, make sure you tell your doctor about any other medications you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take aspirin, products containing aspirin unless your doctor specifically permits this.
Does goserelin stop periods?
Within about three weeks of the first goserelin injection, your oestrogen will be lowered to a level similar to that of a post-menopausal woman (a woman who has been through the menopause) and your periods will normally stop. This effect is generally temporary and will only last for as long as you’re having goserelin.
What is the mechanism of action of goserelin?
Goserelin is a Gonadotropin Releasing Hormone Receptor Agonist. The mechanism of action of goserelin is as a Gonadotropin Releasing Hormone Receptor Agonist. Goserelin is a synthetic decapeptide analog of luteinizing hormone-releasing hormone (LHRH) with antineoplastic activity.
What kind of cancer can goserelin be used for?
(NCI04) A synthetic long-acting agonist of GONADOTROPIN-RELEASING HORMONE. Goserelin is used in treatments of malignant NEOPLASMS of the prostate, uterine fibromas, and metastatic breast cancer.
Which is the chemical formula for goserelin Zoladex?
Goserelin PubChem CID 5311128 Structure Find Similar Structures Chemical Safety Laboratory Chemical Safety Summary (LCSS Molecular Formula C59H84N18O14 Synonyms goserelin Zoladex 65807-02-5 Goserelin a
Which is the generic name for goserelin hormone therapy?
Chemocare.com uses generic names in all descriptions of drugs. Zoladex is the trade name for goserelin. In some cases, health care professionals may use the trade name zoladex when referring to the generic drug name goserelin. Drug type: Goserelin is a hormone therapy.