What are the cellular origins of carcinoma and sarcoma?
Carcinomas arise out of epithelial cells that line the surface and organs of the body, whereas sarcomas arise from connective tissues such as bone, cartilage, fibrous tissue, blood vessels, and nerves.
What are the symptoms of spindle cell sarcoma?
The most commonly reported symptoms of spindle cell sarcoma patients are:
- Bone pain – this may be continuous or may come and go.
- A pathological fracture may occur*– this is a fracture that has occurred due to the weakening of a bone from a disease.
- Swelling.
- The presence of a lump or mass.
- Tenderness in the area.
What cells does sarcoma affect?
About soft-tissue sarcomas
| Name of Sarcoma | Related Normal Tissue Type |
|---|---|
| Fibrosarcoma | Fibroblasts, which are the most common type of cells in connective tissue |
| Gastrointestinal stromal tumor (GIST) | Specialized neuromuscular cells of the digestive tract |
| Kaposi sarcoma | Blood vessels |
| Leiomyosarcoma | Smooth muscle |
What does the beginning of sarcoma look like?
A sarcoma may appear as a painless lump under the skin, often on an arm or a leg. Sarcomas that begin in the abdomen may not cause signs or symptoms until they get very big. As the sarcoma grows bigger and presses on nearby organs, nerves, muscles, or blood vessels, signs and symptoms may include: Pain.
In what tissue would a sarcoma originate?
“Sarcoma” is a term used to describe a whole family of cancers that arise in the body’s connective tissues, which include fat, muscle, blood vessels, deep skin tissues, nerves, bones, and cartilage. Sarcoma is broken down into two types: soft tissue tumors and bone tumors.
What is sarcoma symptoms?
Signs and symptoms of sarcoma include:
- A lump that can be felt through the skin that may or may not be painful.
- Bone pain.
- A broken bone that happens unexpectedly, such as with a minor injury or no injury at all.
- Abdominal pain.
- Weight loss.
What are the symptoms of sarcoma?
Where do sarcomas start?
Sarcoma is a type of cancer that starts in certain parts of the body, like bone or muscle. These cancers start in soft tissues like fat, muscle, nerves, fibrous tissues, blood vessels, or deep skin tissues. They can be found anywhere in the body, but most of them start in the arms or legs.
Where do sarcomas originate?
While sarcomas may arise anywhere in the body, they most often originate in the arms, legs, chest, or abdomen. Sarcomas are often not symptomatic until they are very large and may first be noticed as swelling or a painless lump.