What are the causes of hypospadias?
The causes of hypospadias in most infants are unknown. In most cases, hypospadias is thought to be caused by a combination of genes and other factors, such as things the mother comes in contact with in her environment, or what the mother eats or drinks, or certain medications she uses during pregnancy.
Is hypospadias associated with other defects?
Hypospadias is the most common congenital anomaly affecting the genitals. Its association with other anomalies is rare. It has been reported that other malformations occur in 29.3% of the cases with hypospadias. The more proximal the meatus, the higher the risk for having another associated anomaly.
What is hypospadias and Chordee?
Chordee is a birth defect in boys in which the penis is bent during an erection, which even infants can experience. Males with chordee often have hypospadias, a condition where the opening of the urethra tube through which urine passes is located on the underside of the penis rather than at the tip.
Is hypospadias inherited?
Is hypospadias a genetic disease? Yes, especially in familial and syndromic forms, and hypospadias due to abnormal genital development (phallus or testicular dysgenesis) or associated with a defect of the androgens pathway (20% of the cases).
How does hypospadias cause infertility?
The fold of skin on top of the penis (the foreskin) also forms abnormally. Hypospadias can prevent normal urine flow. Later in life it can cause problems with semen flow. This can lead to not being able to have children (infertility).
Can hypospadias cause infertility?
Hypospadias does not directly cause infertility.
What causes a chordee?
Causes. The precise cause of chordee is unknown. The most common reason is that the penis does not develop properly in the womb. A skin defect, penis abnormality, or other defect is present that results in a curved appearance, which is most evident during erection.
Will hypospadias cause infertility?
Hypospadias can prevent normal urine flow. Later in life it can cause problems with semen flow. This can lead to not being able to have children (infertility).
Can hypospadias affect fertility?
Can hypospadias affect fertility? Hypospadias does not directly cause infertility. However, men with severe hypospadias may be infertile due to accompanying problems with the testes.
How can you prevent hypospadias?
The strategy to prevent hypospadias should be focused on (1) identifying genetic susceptibility prior to pregnancy and (2) identifying and eliminating exposure to potential toxic endocrine disruptors that effect urethral development.