Is there anything like Adequan for humans?
Arteparon is the human equivalent to Adequan and the chemical structure of the two products is identical. Chondroitin sulfate is the most commonly used GAG in these products and is harvested from bovine lung and trachea.
Is Adequan for dogs a steroid?
How is Adequan® Canine different from a non-steroidal anti-inflammatory drug (NSAID)? Adequan® Canine is a prescription formulation PSGAG. It is a disease-modifying osteoarthritis drug (DMOAD) which inhibits cartilage loss in a dog’s joints.
Is adequan safe for long term use?
Since Adequan is so useful in slowing the progression of osteoarthritis, it is reassuring to know that Adequan injections are safe for long-term use in dogs. In order to avoid any pain or inflammation at the injection site, your vet may change the location of the injection each time he or she administers it.
Why isn’t Adequan approved for humans?
It’s just a fact that products intended for use in animals get through the approval process with a different level of scrutiny than that which is directed towards products intended for use in humans.
Is there a generic for Adequan?
There is no generic Adequan® i.m. Adequan i.m. is the ONLY FDA-Approved polysulfated glycosaminoglycan (PSGAG) for the intramuscular treatment of non-infectious degenerative joint disease (DJD) of the carpal and hock joints.
Are there side effects to Adequan for dogs?
When administered properly and at label dosages, Adequan is associated with very few side effects. Although adverse effects are uncommon and usually resolve without treatment, pain or swelling at the injection site has been reported. Delayed blood clotting has also been reported in some dogs receiving Adequan.
How long can a dog use Adequan?
4 weeks
By administering Adequan® Canine twice weekly for up to 4 weeks (maximum of 8 injections), the drug levels are sustained in the synovial joints for an extended period of time —giving the active ingredients time in the joint to help slow the disease progression.
What kind of drug is Polysulfated glycosaminoglycan?
Polysulfated glycosaminoglycan. Polysulfated glycosaminoglycan (PSGAG), sold under the brand name Adequan, is an injectable drug for dogs and horses that is used to alleviate the lameness, pain, and lowered range of motion caused by arthritis. It is made of repeat disaccharide units (comprising hexosamine and hexuronic acid ),…
Where are glycosaminoglycans found in the human body?
Polysulfated glycosaminoglycan (PSGAG) – Patented Topical Wound Management Dressing Chondroprotective agents are natural substances such as glycosaminoglycans that support or enhance the connective tissue matrix and, as such, are found in the chemical composition of connective tissue and soft tissue in humans and animals.
Can you give Polysulfated glycosaminoglycan to a pregnant dog?
Polysulfated glycosaminoglycan should not be used in pets that are allergic to it, or pets with a known or suspected bleeding disorder. It should be used cautiously in pregnant or nursing animals, or pets with kidney or liver dysfunction. Are there any drug interactions I should be aware of?
How does PSGAG affect the synthesis of glycosaminoglycans?
PSGAG also stimulates the synthesis of glycosaminoglycans, hyaluronic acid, and collagen, which increase synovial viscosity. It cannot, however, completely reverse the disappearance of cartilage, nor can it reverse bone loss caused by arthritis.