Is maribavir FDA approved?
The FDA has approved maribavir (Livtencity) for the treatment of adult and pediatric patients aged 12 years and older weighing at least 35 kg who have post-transplant cytomegalovirus (CMV) infection that does not respond to available antiviral treatment.
What is the treatment for CMV virus?
The drug of choice for treatment of CMV disease is intravenous ganciclovir, although valganciclovir may be used for nonsevere CMV treatment in selected cases. Ganciclovir is a nucleoside analogue that inhibits DNA synthesis in the same manner as acyclovir.
What is CVM disease?
Cytomegalovirus (CMV) is a member of the herpes family. In healthy people, it causes a mild flu-like illness that lasts a few days or weeks. In susceptible people, such as those with suppressed immunity or unborn babies, CMV can be a dangerous infection.
How do you contract CMV virus?
People with CMV may pass the virus in body fluids, such as saliva, urine, blood, tears, semen, and breast milk. CMV is spread from an infected person in the following ways: From direct contact with saliva or urine, especially from babies and young children. Through sexual contact.
What’s CMV pregnant?
CMV is a common viral infection, especially among young children. Congenital CMV occurs when the infection is passed across the placenta from a pregnant woman to her developing baby. Some babies with congenital CMV infection show signs of disability at birth, while others are born healthy.
Can CMV cause liver damage?
Liver damage is a characteristic feature of the clinical syndromes caused by cyto- megalovirus (CMV) infection in man. Jaundice and hepatosplenomegaly occur commonly in cytomegalic inclusion dis- ease of the newborn.
Should I be worried about CMV?
CMV infection usually isn’t harmful in healthy adults or children because their immune system protects their bodies from infection. But CMV can cause serious health problems for some, including: Babies who get infected before birth.
Does CMV require isolation?
CMV infection without symptoms is common in infants and young children; therefore, it is unjustified and unnecessary to exclude from school or an institution a child known to be infected. Similarly, hospitalized patients do not need separate or elaborate isolation precautions.