Why would atorvastatin be stopped?
You won’t get any withdrawal symptoms. However, stopping atorvastatin may cause your cholesterol to rise. This increases your risk of heart attacks and strokes. If you want to stop taking your medicine, it’s important to find another way to lower your cholesterol.
Are atorvastatin any good?
Atorvastatin has an average rating of 4.3 out of 10 from a total of 246 ratings on Drugs.com. 29% of reviewers reported a positive effect, while 55% reported a negative effect.
What is the difference between statin and atorvastatin?
Atorvastatin and simvastatin are both effective statin drugs for lowering blood cholesterol. However, atorvastatin is considered a more potent statin. Atorvastatin lasts longer in the body and can be taken in the morning or at night.
Which is safer rosuvastatin or atorvastatin?
Atorvastatin was the safest statin as it resulted in the least number of patients at the end of 2 years of treatment with the new onset of microalbuminuria (10.9%) followed by rosuvastatin (14.3%) and then pravastatin (26.6%).
What vitamins should not be taken with atorvastatin?
A magnesium- and aluminum-containing antacid was reported to interfere with atorvastatin absorption. People can avoid this interaction by taking atorvastatin two hours before or after any aluminum/magnesium-containing antacids. Some magnesium supplements such as magnesium hydroxide are also antacids. St.
What kind of enzyme does atorvastatin inhibit?
Atorvastatin competitively inhibits hepatic hydroxymethyl-glutaryl coenzyme A ( HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a key step in cholesterol synthesis.
What are the side effects of atorvastatin in mice?
The reported LD50 of oral atorvastatin in mice is higher than 5000 mg/kg.[MSDS] In cases of overdose with atorvastatin, there is reported symptoms of complicated breathing, jaundice, liver damage, dark urine, muscle pain, and seizures.
What’s the chemical formula for the Lipitor atorvastatin?
Atorvastatin PubChem CID 60823 Structure Find Similar Structures Chemical Safety Laboratory Chemical Safety Summary (LCSS Molecular Formula C33H35FN2O5 Synonyms atorvastatin 134523-00-5 Cardyl Lipitor
Which is more metabolized Lipitor or HMG CoA?
Lipitor is extensively metabolized to ortho- and parahydroxylated derivatives and various beta-oxidation products. In vitro inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase by ortho- and parahydroxylated metabolites is equivalent to that of Lipitor.