Which tumor marker is used for colorectal cancer?
The most common tumor marker for colorectal cancer is carcinoembryonic antigen (CEA). Blood tests for this tumor marker can sometimes suggest someone might have colorectal cancer, but they can’t be used alone to screen for or diagnose cancer.
Which tumor marker is elevated in colorectal cancer?
Carcinoembryonic antigen (CEA) level: the tumor marker most often used in colorectal cancer.
What is a high CEA level for rectal cancer?
Levels of CEA higher than 20 ng/mL are considered very high. If you have CEA levels this high and you also have symptoms of cancer, it strongly suggests the cancer has not been removed successfully after treatment. It may also suggest that the cancer has metastasized, or spread, to other parts of your body.
What is considered a high cancer marker?
Normal range: < 2.5 ng/ml. Normal range may vary somewhat depending on the brand of assay used. Levels > 10 ng/ml suggest extensive disease and levels > 20 ng/ml suggest metastatic disease.
What is the difference between CEA and CA125?
No significant difference was identified in CA125/CEA ratio vs CEA alone in distinguishing ovarian neoplasms, including benign and malignant, from metastases.
Is CEA elevated in rectal cancer?
CEA is secreted by a variety of solid tumors, including 90% of colorectal cancers (3). As the single most important and reliable serum prognostic biomarker in colorectal cancer, elevated preoperative CEA levels are found to be associated with worse prognosis of colorectal cancer (4–9).
What is a normal CA 125 level?
CA 125 Levels Chart
| CA 125 Levels (units/mL) | Potential Cancer |
|---|---|
| 0 – 35 (normal) | Unlikely to have cancer. 99% of the time, it means no cancer. |
| >35 (high) | Possible cancer. More tests will be needed for a diagnosis. |
How accurate is carcinoembryonic antigen?
Sensitivity of CEA ranged from 17.4 % to 100 %, specificity ranged from 66.1 % to 98.4 %, positive predictive value ranged from 45.8 % to 95.2% and negative predictive value ranged from 74.5 % to 100 %.