What pathogen causes coronary heart disease?
Literature has reported several infectious agents (viruses, bacteria, and parasites) that can be associated with risk of CAD. This association for some of them like Helicobacter pylori (H. pylori), Chlamydia pneumonia (C. pneumoniae), and Cytomegalovirus (CMV) is a very strong.
What causes coronary occlusion?
Most occlusions are caused by either a blood clot or the buildup of fatty plaque in the arteries (atherosclerosis). A blood clot can form at the site of occlusion, or it can travel from another area through the bloodstream and block an artery. That runaway clot is called an embolism.
What is the most common cause of coronary occlusion?
The most common cause of CAD is vascular injury with cholesterol plaque buildup in the arteries, known as atherosclerosis. Reduced blood flow occurs when one or more of these arteries becomes partially or completely blocked.
What is coronary heart disease pathology?
coronary heart disease, also called coronary artery disease or ischemic heart disease, disease characterized by an inadequate supply of oxygen-rich blood to the heart muscle (myocardium) because of narrowing or blocking of a coronary artery by fatty plaques (see atherosclerosis).
Is coronary heart disease a pathogenic disease?
A large body of evidence exists that implicates a number of microbial agents in the pathogenesis of coronary heart disease (CHD). This, if proven, may have far-reaching implications for the prevention and treatment of CHD and other atherosclerotic disease.
What is the microorganism that causes atherosclerosis?
Infectious agents that have been linked to atherosclerotic disease include, but not limited to Chlamydia pneumoniae, Porphyromonas gingivalis, Helicobacter pylori, influenza A virus, hepatitis C virus, cytomegalovirus (CMV), and human immunodeficiency virus (HIV).
What’s a coronary occlusion?
A coronary occlusion is the partial or complete obstruction of blood flow in a coronary artery. This condition may cause a heart attack. In some patients coronary occlusion causes only mild pain, tightness or vague discomfort which may be ignored; however, the myocardium, the muscle tissue of the heart, may be damaged.
What is a coronary thrombosis?
Myocardial infarction (coronary thrombosis or heart attack) results from the complete occlusion (blockage) of one or more coronary arteries. It arises when atherosclerotic plaques rupture, causing platelet activation, adhesion and aggregation with subsequent thrombus formation within the coronary circulation.
What happens when RCA is blocked?
If an artery is substantially blocked, development of collateral circulation (i.e., other smaller vessels) may occur. When this happens, the collateral vessels help to maintain circulation to the area served by the artery in question.
What is the pathophysiology of coronary atherosclerosis?
Coronary artery disease is caused by plaque buildup in the wall of the arteries that supply blood to the heart (called coronary arteries). Plaque is made up of cholesterol deposits. Plaque buildup causes the inside of the arteries to narrow over time. This process is called atherosclerosis.