What is ursodeoxycholic used for?
About ursodeoxycholic acid
| Type of medicine | A bile acid |
|---|---|
| Used for | Dissolving gallstones A type of liver disease known as primary biliary cholangitis (cirrhosis) |
| Also called | Ursodiol (in US); Destolit®; Ursofalk®; Ursogal®; Ursonorm®, Cholurso® |
| Available as | Capsules, tablets, and liquid medicine |
Does Urso lower bile acids?
Unlike other primary bile acids, ursodiol has little agonist activity with FXR, the bile acid sensing nuclear receptor. As a consequence, ursodiol has little effect on cholesterol and lipid synthesis and is effective in reducing the cholesterol saturation of bile and in dissolving cholesterol gallstones.
How does ursodiol work for cholestasis?
To soothe intense itching, your pregnancy care provider may recommend: Taking a prescription drug called ursodiol (Actigall, Urso, Urso Forte), which helps to lower the level of bile in your blood. Other medications to relieve itching may also be an option.
Can ursodiol cause liver problems?
Ursodiol side effects liver problems–nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or. signs of a new infection–sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, skin sores, trouble swallowing.
Is Urso an immunosuppressant?
Ursodeoxycholic acid (URSO) treatment reduces intracellular hydrophobic bile acid levels and thereby may have a cytoprotective effect on cell membranes. URSO may also act as an immunomodulating agent.
Can ursodeoxycholic acid cause kidney problems?
Ursodeoxycholic acid is a bile acid secreted in humans that helps eliminate cholesterol and dissolve fats. It is currently approved for clinical use and treatment of gall stones and liver disease. In laboratory and animal studies Ursodeoxycholic acid reduces albuminuria and prevent progression of kidney damage.
What is the side effect of ursodeoxycholic acid?
Ursodiol side effects pain or burning when you urinate; liver problems–nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or.