What is the drug of choice for angina?
Nitrates or beta blockers are usually preferred for initial treatment of angina, and calcium channel blockers may be added if needed. The number and type of medications used are often tailored to how frequently angina occurs in an average week.
Which classes of drugs are used in the treatment of angina pectoris?
Common drug classes used to treat angina are beta blockers, calcium channel blockers, anticoagulants, nitrates, antiplatelet drugs, calcium channel blocker / statin combinations, and anti-anginals.
Is trimetazidine safe?
Trimetazidine has been generally very well tolerated in clinical trials and usually only isolated cases of adverse events (ADRs—adverse drug reactions) were observed during trimetazidine treatment (mainly gastrointestinal disturbances, vomiting, nausea) [61].
What is first line treatment for angina?
Beta-blockers are an appropriate first-line medical treatment to relieve the symptoms of angina. Calcium channel blockers or long-acting nitrates may be appropriate for those who do not tolerate or who have contraindications to beta-blockers.
How long can you take nitroglycerin?
1 tablet may be used every 5 minutes as needed, for up to 15 minutes. Do not take more than 3 tablets in 15 minutes.
How long does angina medication take to work?
Angina medicines There are two types of nitrate medicines. Short-acting nitrate medicines are absorbed through the lining of your mouth into your bloodstream to relieve angina symptoms within a few minutes. This is why they are called ‘short-acting’.
How long should trimetazidine be taken?
In conclusion, treatment with trimetazidine added to the usual treatment for up to 18 months was well tolerated and induced functional improvement in patients with ischaemic dilated cardiomyopathy. Trimetazidine treatment was associated with a significant improvement of LV function and the remodelling process.
Does amlodipine help angina?
Amlodipine is a medicine used to treat high blood pressure (hypertension). If you have high blood pressure, taking amlodipine helps prevent future heart disease, heart attacks and strokes. Amlodipine is also used to prevent chest pain caused by heart disease (angina). This medicine is only available on prescription.
Is nitroglycerin a vasodilator?
It is also used just before activities that may cause episodes of angina in order to prevent the angina from occurring. Nitroglycerin is in a class of medications called vasodilators. It works by relaxing the blood vessels so the heart does not need to work as hard and therefore does not need as much oxygen.
How much nitro can you take in 24 hours?
Adults—2.5 to 6.5 milligrams (mg) 3 to 4 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.