What is herbal drug and food interaction?
Interactions between food and drugs may inadvertently reduce or increase the drug effect. Some commonly used herbs, fruits as well as alcohol may cause failure of the therapy up a point of to serious alterations of the patient’s health.
Does Chlorpropamide cause hyponatremia?
Chlorpropamide administration was associated with hyponatremia and serum hypoosmolality, continued sodium excretion despite hyponatremia and an impaired ability to dilute urine maximally and to excrete a water load.
Which herbs Cannot be taken together?
When herbals hurt
- Fenugreek. People with diabetes should watch out for this herb, Gorin noted.
- Melatonin. Don’t mix this with sedatives such as benzodiazepines, narcotics, and some antidepressants.
- St. John’s wort.
- Gingko biloba.
- Echinacea.
- Schisandra.
Can herbal supplements interact with each other?
Even though herbal supplements may be from plant or herb sources, the active ingredients can still be potent chemicals. Because of this, herbal supplements can have drug interactions, even with each other or with food or alcohol.
What is drug disease interaction?
Drug-disease interactions (DDSIs) are situations where the pharmacotherapy used to treat a disease causes worsening of another disease in a patient (Merck Manual Consumer Version). In these circumstances drugs should be avoided (i.e., are contra-indicated), adjusted or accompanied by extra monitoring.
What are drug food interactions?
Share. A drug-food interaction occurs when your food and medicine interfere with one another. Interactions can happen with both prescription and over-the-counter medicines. These include antacids, vitamins, and iron pills. Not all medicines are affected by food.
What happens when one drug interacts with another?
Drug interactions may lead to an increase or decrease in the beneficial or the adverse effects of the given drugs. When a drug interaction increases the benefit of the administered drugs without increasing side effects, both drugs may be combined to increase the control of the condition that is being treated.
Are there any side effects to taking chlorpropamide?
Chlorpropamide should be used with caution in patients with hepatic disease. Renal impairment or hepatic disease can cause elevations in chlorpropamide drug concentrations and hepatic disease can reduce gluconeogenic capacity; both problems increase the risk of hypoglycemia.
How is chlorpropamide used in the treatment of CDI?
Chlorpropamide (Diabinese) is an oral sulfonylurea drug used for the treatment of hyperglycemia in humans. Largely by chance, chlorpropamide has also been found to be efficacious in treating humans with CDI and has been found to reduce urine output 30% to 70% in humans afflicted with partial CDI.
Can you take chlorpropamide while breast feeding?
If you are breast-feeding. Do not breast-feed while you take chlorpropamide. This is not a list of all drugs or health problems that interact with chlorpropamide. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems.
Which is a mechanism for potentiation of chlorpropamide?
Inhibition of prostaglandin E 2 (PGE 2) synthesis, thereby removing an antagonist of AVP, has also been proposed as a mechanism for chlorpropamide potentiation.