What is granular cast?

What is granular cast?

Granular casts are generally the result of degeneration of cells in cellular casts [I3]. Their significance lies with the cast from which they were formed. Granular casts may also be the result of direct ag- gregation of serum proteins and other sub- stances into a matrix of Tamm-Horsfall mucoprotein.

What is coarse granular cast?

Granular casts, as the name implies, have a textured appearance which ranges from fine to coarse in character. Since they usually form as a stage in the degeneration of cellular casts, the interpretation is the same as that described for cellular casts.

What is waxy cast?

Casts are clusters of urinary sediment elements (red blood cells, white blood cells, fat bodies, etc.) wrapped in a protein matrix. Cast formation necessarily occurs in the kidney tubules, and the contents of the casts indicate the nature of the abnormalities occurring in the kidney itself.

What do urine casts mean?

Urinary casts are microscopic cylindrical structures produced by the kidney and present in the urine in certain disease states. They form in the distal convoluted tubule and collecting ducts of nephrons, then dislodge and pass into the urine, where they can be detected by microscopy.

Where are casts formed?

Casts are cylindrical bodies formed either in the distal convoluted tubules or the collecting ducts of the kidney. Since the walls of the tubule act as a mold for cast formation, the width of the tubule determines the width of the cast.

What do cellular casts look like?

Fatty casts Formed by the breakdown of lipid-rich epithelial cells, these are hyaline casts with fat globule inclusions, yellowish-tan in color. If cholesterol or cholesterol esters are present, they are associated with the “Maltese cross” sign under polarized light.

What is hyaline casts urine?

Hyaline casts are a type of urinary cast, which is a cluster of urinary particles, such as cells, fat bodies, or microorganisms, held together by a protein matrix and found in the urine.

What does casted mean?

1a : to cause to move or send forth by throwing cast a fishing lure cast dice. b : direct cast a glance. c(1) : to put forth the fire casts a warm glow cast light on the subject cast a shadow. (2) : to place as if by throwing cast doubt on their reliability.

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