What is danazol tablet used for?
Danazol is used to treat endometriosis (a condition in which the type of tissue that lines the uterus [womb] grows in other areas of the body and causes infertility, pain before and during menstrual periods, pain during and after sexual activity, and heavy or irregular bleeding)..
Why is danazol used to treat endometriosis?
Danazol acts by inhibiting the midcycle follicle-stimulating hormone (FSH) and luteinizing hormone (LH) surges and preventing steroidogenesis in the corpus luteum. It is the most extensively studied agent for endometriosis.
Is danazol still used for endometriosis?
Danazol is an effective treatment for endometriosis, and has the same effectiveness as the other hormonal treatments. However, it has many androgenic (male-like) side effects, including weight gain, increased body hair and acne.
Does danazol cause infertility?
It can cause cysts and infertility. Danazol is a hormone that produces male characteristics as well as weight gain and acne. It does, however, relieve the painful symptoms of endometriosis, although the side effects can be unacceptable.
What are the side effects of tamoxifen?
Side effects of tamoxifen may include:
- Menopause-like symptoms, including hot flashes, night sweats and vaginal dryness.
- Weight gain (more common) or fluid retention (edema).
- Irregular or loss of menstrual periods.
- Leg swelling.
- Nausea.
- Vaginal discharge.
- Skin rash.
- Erectile dysfunction .
Does danazol increase testosterone?
Danazol is known to cause marked suppression of sex hormone binding globulin (SHBG) levels in plasma and to increase the proportion of plasma testosterone unbound to protein but the effect on the concentration of total and free testosterone is unclear.
Which birth control pill is best for endometriosis?
Birth control can help treat some of endometriosis symptoms like pain and heavy period bleeding. Estrogen-progesterone birth control pills are considered the best at treating endometriosis.
Is danazol a steroid?
Danocrine (danazol) is a synthetic steroid with multiple and diverse biologic effects. It exerts these effects by binding to steroid transport proteins in the circulation and to specific receptors in target tissues. Centrally, danazol inhibits gonadotropins, suppressing gametogenesis and steroidogenesis.