What is acinic cell carcinoma of the parotid gland?
Acinic cell carcinoma (ACC) is a low-grade malignant salivary neoplasm that constitutes approximately 17% of primary salivary gland malignancies. In the head and neck region, the parotid gland is the predominant site of origin and women are usually more frequently diagnosed than men.
Can acinic cell carcinoma be cured?
While surgical excision is usually done to treat acinic cell carcinoma, modern research has examined the possibility of radiotherapy as a treatment procedure. This is due to the treatment hypothesis that parotid cancer patients would generally demonstrate survival with adjuvant radiotherapy.
How bad is acinic cell carcinoma?
IMPORTANCE. Acinic cell carcinoma is a rare salivary neoplasm that is generally associated with a good prognosis, although a subset of patients develops local and distant recurrences. Given the rarity of the disease, factors to identify patients at risk for recurrences or decreased survival are not clearly defined.
What causes squamous cell carcinoma of the parotid gland?
Squamous cell carcinomas metastatic to parotid region can occur as direct extensions from tumours in external ear or periaural skin or as metastasis to the intraparotid and periparotid lymph nodes.
Does acinic cell carcinoma spread?
Although acinic cell carcinomas rarely metastasize, they have a high tendency to recur locally if they are incompletely excised. We describe a patient with acinic cell tumor arising in the parotid gland, with metastases to the contralateral orbit, submandibular salivary gland, and submandibular lymph node.
What does Acinic mean?
Definitions of acinic. adjective. pertaining to one of the small sacs (as in a compound gland)
Should a parotid tumor be removed?
Treatment Surgery is recommended for almost all parotid gland tumors, whether cancerous or benign. Although most tumors grow slowly and are non-cancerous, they will often continue to grow and occasionally can become cancerous. Treatment of a parotid tumor generally requires removing the parotid gland (parotidectomy).
Can acinic cell carcinoma spread to brain?
Acinic cell carcinoma represents approximately 5% to 17% of all salivary gland cancers1,2 and can very rarely arise from the lacrimal gland. Spiro et al7 reported a distant metastasis rate of 12%, mainly to lung, bone, and brain.
What is the meaning of Sialadenolithiasis?
Term. Stone in a salivary gland. Definition. Sialadenolithiasis.
What causes a Sialolith?
First, dehydration and poor eating habits are considered culprits that can lead to the formation of salivary duct stones. Not drinking enough fluids can make your saliva more concentrated and not eating enough can cause a reduction in your saliva production, forming salivary duct stones.
Is the parotid gland related to acinic cell carcinoma?
A gradual mass progression of the terminal end of the parotid gland usually affected. Almost 17 percent of the primary salivary gland carcinoma is related to the Acinic Cell Carcinoma.
Where does acinic cell carcinoma occur in the salivary gland?
Acinic Cell Carcinoma is a low-grade neoplasm occurs on the epithelial cell lining of the salivary gland. A gradual mass progression of the terminal end of the parotid gland usually affected. Almost 17 percent of the primary salivary gland carcinoma is related to the Acinic Cell Carcinoma.
How is acinic cell carcinoma ( ACC ) treated?
Acinic cell carcinoma (ACC) is a rarest form of low-grade malignant salivary neoplasm in which the predominant site is the parotid gland and women are usually more frequently diagnosed than men. Surgical excision is the main treatment of this malignant neoplasm. Other treatment modalities such as radiotherapy may be indicated in some cases.
What kind of surgery is needed for parotid gland cancer?
The standard of care in primary ACC of parotid gland is the complete surgical removal of the tumor, total or subtotal parotidectomy [ 2 ].