What does adduct mean?
: to draw (something, such as a limb) toward or past the median axis of the body also : to bring together (similar parts) adduct the fingers.
What is adduct in LC MS?
Adduct ions are prevalent in LC-MS analyses and can come from any number of sources. An adduct ion is any ion formed by adduction of an ionic species to a molecule, and can be present under all modes of ionization (e.g. ESI, APCI etc.) and under different ionization polarities (positive or negative ionization).
What is a protein adduct?
Protein adducts are covalent. modifications resulting from reactions between electrophiles and nucleophilic sites in proteins, such as. the N-terminus or the amino acid side chains containing sulfhydryl or amine functionalities.
How adduct is formed?
An adduct is a product formed at the end of an addition reaction. This is a reaction in which two or more molecules react and combine to form one larger product. This type of reaction can only occur between chemical compounds which have multiple bonds – compounds like alkenes (double bonds) and alkynes (triple bonds).
What does adduction mean in medical terms?
Adduction: Movement of a limb toward the midline of the body. The opposite of adduction is abduction.
What causes DNA adducts?
DNA adducts are a form of DNA damage caused by covalent attachment of a chemical moiety to DNA. Adducts that are not removed by the cell can cause mutations that may give rise to cancer. They are frequently used as biomarkers for chemical hazard exposure or cancer therapy efficacy.
What are ESI adducts?
Abstract. Adduct formation is a common ionization method in electrospray ionization mass spectrometry (ESI/MS). However, this process is poorly understood and complicated to control. We demonstrate possibilities to control adduct formation via mobile phase additives in ESI positive mode for 17 oxygen and nitrogen bases …
What is cysteine adduct?
Although cysteine is the most acrolein-reactive residue, cysteine-acrolein adducts are difficult to identify in vitro and in vivo. Adduct formation with the side chains of other amino acid residues (lysine and histidine) was much slower than cysteine and required higher acrolein concentration.
What does adduct mean in anatomy?
What is adduction example?
Adduction is the movement of a body part toward the body’s midline. So, if a person has their arms straight out at the shoulders and brings them down to their sides, it is adduction. Closing arms to the chest or bringing knees together are other examples of adduction.
What is adduction and abduction?
Abduction and adduction are terms that refer to certain body motions or movements. With abduction, limbs (arms, legs or fingers) are moved away from your body’s midline. Adduction, however, refers to moving your limbs closer to the midline.
Which is the correct definition of an adduct?
An adduct (from the Latin adductus, “drawn toward” alternatively, a contraction of “addition product”) is a product of a direct addition of two or more distinct molecules, resulting in a single reaction product containing all atoms of all components. The resultant is considered a distinct molecular species. Click to see full answer.
How does a mass spectrometer tell the mass of a compound?
Modern mass spectrometers easily distinguish (resolve) ions differing by only a single atomic mass unit (amu), and thus provide completely accurate values for the molecular mass of a compound.
What happens to elemental compositions after remove of adducts?
After removal of adducts you can enter your results into the Seven Golden Rules software and find highly probable elemental compositions. These elemental compositions can be matched against molecular compound databases to get a first hint of a possible isomer structure.
How are molecules bombarded by electrons in mass spectrometry?
Here molecules of the sample (black dots) are bombarded by electrons (light blue lines) issuing from a heated filament. This is called an EI (electron-impact) source. Gases and volatile liquid samples are allowed to leak into the ion source from a reservoir (as shown).