What are the long term side effects of aromatase inhibitors?
Aromatase inhibitors tend to cause fewer serious side effects than tamoxifen, such as blood clots, stroke, and endometrial cancer. But aromatase inhibitors can cause more heart problems, more bone loss (osteoporosis), and more broken bones than tamoxifen, at least for the first few years of treatment.
How long can you take Aromasin?
In most cases, you’ll take Aromasin for 2 or 3 years. Doctors may recommend that some women take it for a longer time.
How long should you stay on exemestane?
This will depend on your individual circumstances, but exemestane is usually taken for five to ten years. Some people start taking exemestane after a few years of taking the hormone therapy drug tamoxifen.
Does Aromasin cause liver damage?
Cases of acute liver failure have been reported in women on exemestane therapy, but the relationship of the injury to the aromatase inhibitor has not been well defined.
Does memory improve after stopping letrozole?
The substudy showed significant improvement in cognition after cessation of therapy. The finding was consistent across all cognitive tasks and consistent in women taking either tamoxifen or letrozole at the 5-year time point. The observed effect size was moderate for the change in overall cognition.
Does Aromasin make you tired?
SIDE EFFECTS: Hot flashes, hair loss, joint/bone/muscle pain, tiredness, unusual sweating, nausea, diarrhea, dizziness, and trouble sleeping may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
Is Aromasin permanent?
By binding itself, either temporarily (Arimidex, Femara) or permanently (Aromasin) to aromatase so that it becomes dysfunctional, and can’t turn androgen into estrogen.
Is Aromasin better than letrozole?
Researchers that compared Aromasin and Femara used in early breast cancer found that the two drugs worked equally well. With Aromasin, 88% of women lived for at least 5 years without their breast cancer returning, while 89.4% of women taking Femara lived for at least 5 years without their breast cancer returning.
What is the success rate of exemestane?
As first-line treatment, once daily exemestane 25 mg elicited objective and overall success rates of 42 and 58%, compared with 16 and 31% for once daily tamoxifen 20 mg. Exemestane was generally well tolerated in clinical trials at once daily dosages up to 600 mg.
How long does it take for Aromasin to lower estrogen?
After a single dose of exemestane 25 mg, the maximal suppression of circulating estrogens occurred 2 to 3 days after dosing and persisted for 4 to 5 days.
Does Aromasin cause weight gain?
Taking Aromasin may cause weight gain. In studies of the drug, weight gain occurred when Aromasin was used to treat advanced breast cancer. If you gain weight while taking Aromasin, you shouldn’t stop taking the drug. Instead, talk with your doctor.
Does Aromasin cause hair loss?
You may have some hair loss or thinning while taking exemestane. However, your hair should return to the way it was before treatment when you stop taking exemestane. A small number of women notice an increase in downy facial hair. Some people also report a skin rash.
What should I avoid while taking Aromasin?
Oranges&tangerines
Are there any risks in taking Aromasin?
For this reason, Aromasin can increase your risk of developing osteoporosis and bone fractures and is not recommended for women who have not reached menopause because it can cause irregular periods and infertility problems in women who are still having menstrual periods.
Does Aromasin have any withdrawal effects?
A Verified Doctor answered. No: Aromasin (exemestane) is not a habit-forming drug. Therefore it typically does not have withdrawal effects.
Is cough or hoarseness a side effect of Aromasin?
Aromasin side effects. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: More common. Cough or hoarseness; difficult or labored breathing; fever or chills