What are quinine tablets taken for?
Quinine is used alone or with other medications to treat malaria (a serious or life-threatening illness that is spread by mosquitos in certain parts of the world). Quinine should not be used to prevent malaria. Quinine is in a class of medications called antimalarials.
What is Quinine sulphate?
About quinine
Type of medicine | An antimalarial medicine |
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Used for | Treatment of night-time leg cramps |
Also called | Quinine bisulfate, quinine dihydrochloride, quinine sulfate |
Available as | Tablets |
How do you take quinine sulfate?
falciparum malaria in adults: Orally, 648 mg (two capsules) every 8 hours for 7 days [see Clinical Studies (14)].
- Quinine Sulfate Capsules, USP should be taken with food to minimize gastric upset [see Clinical Pharmacology (12.3)].
- Quinine-induced thrombocytopenia is an immune-mediated disorder.
How much quinine should you take a day?
Adults and children 16 years of age and older—648 milligrams (mg) (2 capsules) every 8 hours for 7 days. Children younger than 16 years of age—Use and dose must be determined by your doctor.
How much quinine can you take daily?
Is quinine bad for liver?
The hepatotoxicity of quinine is usually mild and resolves within 1 to 4 weeks of stopping. In many instances, jaundice and liver test abnormalities may worsen for a few days after stopping quinine, but fatalities have not been reported, and recovery is usually rapid.
What are side effects of quinine sulfate capsules?
See full prescribing information for QUININE SULFATE CAPSULES. Quinine sulfate use for the treatment or prevention of nocturnal leg cramps may result in serious and life-threatening hematologic reactions, including thrombocytopenia and hemolytic uremic syndrome/thrombotic thrombocytopenic purpura (HUS/TTP).
How big is a quinine sulfate gelatin capsule?
Quinine Sulfate Capsules USP, 324 mg are supplied as clear transparent size ‘0’ hard gelatin capsule filled with white to off-white powder and imprinting ‘AMNEAL’ on the cap and ‘811’ on the body. Quinine sulfate capsules are contraindicated in patients with the following: Prolonged QT interval.
Is it safe to give quinine sulfate to infants?
There is limited information on the safety of quinine in breastfed infants. No toxicity was reported in infants in a single study where oral quinine sulfate (10 mg/kg every 8 hours for 1 to 10 days) was administered to 25 lactating women.
What is the half life of quinine sulfate?
The elimination half-life is about 11 hours in healthy subjects but may be prolonged in patients with malaria. Small amounts of quinine also appear in the bile and saliva. Quinine crosses the placenta and is excreted in the breast milk. 5.3 Preclinical safety data