Is Klatskin tumor curable?
As Klatskin tumors are typically resistant to chemotherapy and radiotherapy, surgical resection of the tumor is the only curative treatment but it is not always an option in those patients with widespread metastasis.
Can cholangiocarcinoma go into remission?
So far, several cases have been reported, in which advanced cholangiocarcinoma was completely treated with gemcitabine chemotherapy in Japan,17-20 although only one of them has shown complete remission histopathologically.
What chemo is used for cholangiocarcinoma?
The standard chemotherapy drugs for bile duct cancer are gemcitabine (Gemzar®) and cisplatin. Other drugs sometimes used include fluorouracil (also called 5-FU), oxaliplatin (Eloxatin®), and capecitabine (Xeloda®).
What causes Mirizzi syndrome?
Mirizzi syndrome is defined as common hepatic duct obstruction caused by extrinsic compression from an impacted stone in the cystic duct or infundibulum of the gallbladder [1-3]. Patients with Mirizzi syndrome can present with jaundice, fever, and right upper quadrant pain.
Is Klatskin tumor hereditary?
The cause of Klatskin tumors is unknown. Studies suggest that a combination of genetic, environmental, and lifestyle factors (multifactorial) likely influence whether a person will develop cholangiocarcinoma. Because Klatskin tumors are often discovered after they have spread, they can be challenging to treat.
What is the bismuth Corlette classification for cholangiocarcinoma?
Bismuth-Corlette classification is a classification system for perihilar cholangiocarcinomas: Type I: limited to the common hepatic duct, below the level of the confluence of the right and left hepatic ducts Type II: involves the confluence of the right and left hepatic ducts
Can a bismuth neoplasm be performed on a type 1 patient?
In type I patients, resection of the biliary tract alone provides a curative resection. In type II the neoplasm involves the confluence, dividing the left and right ducts, and frequently the biliary ducts of the caudate lobe. In order to obtain a radical resection (R0) Bismuth suggests biliary resection associated with caudate lobe resection.
What kind of mass is bismuth Corlette Type IIIA?
The hilar mass extends to involve the branches of right hepatic duct (arrow), consistent with Bismuth Corlette Type IIIa. The mass involves the branches of right hepatic duct (arrow).
Can a bismuth resection be performed on a caudate lobe?
In order to obtain a radical resection (R0) Bismuth suggests biliary resection associated with caudate lobe resection. In type IIIa and IIIb, resection of the biliary tract does not guarantee a curative resection and therefore major hepatic resection must be associated.