Is hemoglobin affected by lipemia?
Lipemia interferes with the accurate determination of hemoglobin, or Hb, by spectroscopy on most hematology analyzers, but it does not generally interfere with determinations (especially impedance based) of red blood cell count, white blood cell count, and platelet count.
What results are affected by lipemia?
Conclusion: Lipemia causes clinically significant interferences for phosphorus, creatinine, total protein and calcium measurement and those interferences could be effectively removed by ultracentrifugation.
How lipemia affect CBC?
Q: What CBC parameters are affected when the specimen is lipemic? A: Lipemia in a blood specimen used for clinical evaluation can cause significant interference with obtaining accurate test values. Lipemia creates turbidity of a sample and is a result of the accumulation of lipid particles.
Does lipemia affect sodium?
Considering 0-350 mg% of triglyceride as the reference, electrolytes concentration mostly decreased over increasing lipemia. Beyond triglyceride concentration of 1550 mg%, the sodium concentration obtained from two instruments varied significantly.
How do you fix lipemia?
Centrifugation. A recommended procedure for treating lipemic samples is centrifugation using ultracentrifuge which effectively removes lipids and allows measurement of large number of analytes (42,43). However, due to the high cost, this equipment it is not available in a large number of laboratories.
What is slight lipemia?
Lipemia is presence of a high concentration of lipids (or fats) in the blood. When donated blood is lipemic it causes the plasma-containing products to have a milky appearance.
How do you remove serum lipemia?
Conclusions: High-speed centrifugation (10,000×g for 15 minutes) can be used instead of ultracentrifugation to remove lipemia in serum/plasma samples. LipoClear and 1,1,2-trichlorotrifluoroethane are unsuitable as they interfere with the measurement of certain parameters.
What does it mean if your blood is lipemic?
What causes lipemic?
The most common cause of lipemia is nonfasting, with recent ingestion of lipid-containing meal. More severe lipemia results from a disease condition causing hypertriglyceridemia (eg, diabetes, genetic hyperlipidemia) or recent intravenous infusion of a lipid emulsion.
Does lipemia affect MCH?
Lipemia interferes with hematology tests by the following mechanism by light scattering. This affects the following results: This will manifest as a high mean cell hemoglobin (MCH) and mean cell hemoglobin concentration (MCHC) so these results are often cancelled.