Does Neisseria produce beta-lactamase?
We identified in 2017 at the National Reference Center for Meningococci in Paris, France, an invasive isolate of Neisseria meningitidis that produced a beta-lactamase.
Is Neisseria gonorrhoeae beta-lactamase positive?
gonorrhoeae isolates resistant to thiamphenicol (MIC ≥ 1.0 μg/ml) were beta-lactamase positive. It appears that strains of N. gonorrhoeae from Jakarta which were resistant to thiamphenicol have a greater correlation with PPNG or PPNG-TRNG than with chromosomally mediated resistance to penicillin or tetracycline.
Is Neisseria negative?
Some Neisseria species, e.g., Neisseria cinerea, produce acid from carbohydrates but rapidly overoxidize the acid to carbon dioxide, with the result that acid does not accumulate in the reaction tube although the carbohydrate has been used; N. cinerea is considered to be glucose-negative.
What are Neisseria infections?
Neisseria gonorrhoeae infections may present as a broad range of symptoms and can affect urogenital, anorectal, pharyngeal, and conjunctival areas. Severe cases can lead to disseminated gonococcal infections, endocarditis, and meningitis; and in women, to pelvic inflammatory disease (PID).
Is Neisseria meningitidis beta-lactamase positive?
meningitidis was reported in Canada was in 1983. 15 The isolate, designated M1-221, was described as β-lactamase positive, with a penicillin MIC of 256 mg/L. This N. meningitidis isolate contained two plasmids of 4.5 and 24.5 MDa in size, similar to the sizes of plasmids found in penicillinase-producing N.
Is vancomycin effective against Neisseria?
Vancomycin is primarily effective against gram-positive bacteria (in particular, Staphylococcus spp. and streptococci), enterococci (E. faecium and E. faecalis), and Neisseria spp.
Does gonorrhea produce beta-lactamase?
gonorrhoeae is naturally susceptible to β-lactam antibiotics, and penicillin-resistant isolates can be explained by two major mechanisms: one is based on the modification of penicillin binding proteins (PBPs), which are the target of β-lactam antibiotics, and the other involves the production of TEM-1 β-lactamase.
Is Neisseria Gram positive or negative?
Structure. Neisseria species are Gram-negative cocci, 0.6 to 1.0 μm in diameter. The organisms are usually seen in pairs with the adjacent sides flattened. Pili, hairlike filamentous appendages extend several micrometers from the cell surface and have a role in adherence.
Is Neisseria sicca Gram positive or negative?
Neisseria sicca is a gram-negative diplococcus found as nor- mal human oral and upper respiratory tract flora; it is considered one of the commensal Neisseria species.
Is Haemophilus Gram positive or negative?
Chapter 9: Identification and Characterization of Haemophilus influenzae. H. influenzae are small, pleomorphic, gram-negative bacilli or coccobacilli with random arrangements.
What does beta-lactamase negative mean?
When beta-lactamase-negative, ampicillin-resistant (BLNAR) strains were defined as those for which the ampicillin MIC was > or = 4.0 microg/ml, 5 to 44% of our selected strains were BLNAR depending on the medium and/or test method used.